PEX12 and ACSL5

Data Source:
BioGRID (two hybrid)

		PEX12	ACSL5
Description		peroxisomal biogenesis factor 12	acyl-CoA synthetase long chain family member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding	Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Arachidonate-CoA Ligase Activity
	Biological Process	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination	Long-chain Fatty Acid Metabolic Process Lipid Biosynthetic Process Positive Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Long-chain Fatty-acyl-CoA Biosynthetic Process
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Amyotrophic lateral sclerosis ( 32968195) Basophil percentage of white cells ( 32888494) High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494)
Interacting Genes		36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA	13 interacting genes: AQP6 CREB3 EBAG9 FBXO7 PEX12 RETREG3 SELENOI SLC10A1 SLC10A6 SLC16A7 SLC35C2 SLC7A14 TMEM14B
Entrez ID		5193	51703
HPRD ID		03455	16139
Ensembl ID		ENSG00000108733	ENSG00000197142
Uniprot IDs		O00623	Q9ULC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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