PEX12 and CLDN10

Data Source:
BioGRID (two hybrid)

		PEX12	CLDN10
Description		peroxisomal biogenesis factor 12	claudin 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex	Cytoplasm Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination	Ion Transport Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Regulation Of Ion Transport Bicellular Tight Junction Assembly
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	Tight junction interactions
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Dental caries (decayed and filled deciduous teeth) ( 31533690) Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483) Psychosis proneness (hypomanic personality scale) ( 28525603)
Interacting Genes		36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA	11 interacting genes: BEST2 CISD2 HSD17B13 HTR4 LMNA OPRM1 PEX12 REEP1 TMEM14B TMEM9 VKORC1
Entrez ID		5193	9071
HPRD ID		03455	13063
Ensembl ID		ENSG00000108733	ENSG00000134873
Uniprot IDs		O00623	P78369
PDB IDs
Enriched GO Terms of Interacting Partners?
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