MORF4L1 and MRPL12

Data Source:
BioGRID (two hybrid)

		MORF4L1	MRPL12
Description		mortality factor 4 like 1	mitochondrial ribosomal protein L12
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Sin3 Complex Nuclear Speck NuA4 Histone Acetyltransferase Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	Protein Binding Protein N-terminus Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Chromatin Silencing Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation	Mitochondrial Transcription Positive Regulation Of Transcription, DNA-templated Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		HATs acetylate histones	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254 30104761 33020668) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730)	LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Refractive error ( 32231278) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		76 interacting genes: APP ARID3A ARRDC3 BEND7 BEX5 CALM1 CAMK2B CEP57L1 CWC27 DMAP1 DRAP1 DYSF EP300 FAM13C FAM9B FBXO16 FHL3 FXR2 GMCL1 GOLGA2 GOLGA6A GSC2 H3-4 HINFP HMBOX1 IKZF1 KPNA2 L3MBTL3 LHX2 LMNA LZTS2 MEOX1 MEOX2 MRFAP1 MRFAP1L1 MRGBP MRPL12 MSL1 NAB2 NAV2 NECAB1 NKD1 NMI PBXIP1 PHF12 PIBF1 PICK1 PLEKHA3 PSMC1 RACGAP1 RB1 RCBTB2 REL SH3GLB2 SYN3 TEPSIN TEX11 TFCP2 THAP1 TLE5 TNIP1 TNNT1 TNNT2 TRIM41 TULP3 UBP1 VPS26A ZBTB10 ZBTB26 ZBTB43 ZBTB8B ZBTB9 ZC3H7A ZNF276 ZNF438 ZNF449	24 interacting genes: CBX3 COX6A2 EFCAB2 EFEMP2 EXOC3L2 FBLN1 KRTAP10-1 MAPRE3 MICOS10-NBL1 MORF4L1 MORF4L2 NBL1 NTAQ1 NTM OLIG1 POLR1D PPP1R16A RARG SAT1 SEPTIN1 TMEM51 TRIM59 TXNDC9 ZNF76
Entrez ID		10933	6182
HPRD ID		09532	03849
Ensembl ID		ENSG00000185787	ENSG00000262814
Uniprot IDs		Q9UBU8	P52815
PDB IDs		2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE	6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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