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TIAM1 and EFNB1
Data Source:
HPRD
(in vivo, in vitro)
TIAM1
EFNB1
Description
TIAM Rac1 associated GEF 1
ephrin B1
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Microtubule
Plasma Membrane
Cell-cell Junction
Membrane
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ruffle Membrane
Neuronal Cell Body
Dendritic Spine
Cell-cell Contact Zone
Axonal Growth Cone
Main Axon
Synapse
Glutamatergic Synapse
Extrinsic Component Of Postsynaptic Density Membrane
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane Raft
Synapse
Extracellular Exosome
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Microtubule Binding
Lipid Binding
Kinase Binding
Receptor Tyrosine Kinase Binding
Protein Binding
Ephrin Receptor Binding
Biological Process
Cardiac Muscle Hypertrophy
Apoptotic Process
Cell-matrix Adhesion
G Protein-coupled Receptor Signaling Pathway
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Population Proliferation
Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Epithelial To Mesenchymal Transition
Cell Migration
Rac Protein Signal Transduction
Positive Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Cellular Protein-containing Complex Assembly
Response To Cocaine
Positive Regulation Of Apoptotic Process
Positive Regulation Of JUN Kinase Activity
Ephrin Receptor Signaling Pathway
Positive Regulation Of Axonogenesis
Regulation Of Small GTPase Mediated Signal Transduction
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Dendritic Spine Morphogenesis
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of ERK1 And ERK2 Cascade
Protein Localization To Membrane
Activation Of GTPase Activity
NMDA Selective Glutamate Receptor Signaling Pathway
Positive Regulation Of Schwann Cell Chemotaxis
Regulation Of Dopaminergic Neuron Differentiation
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Neuron Projection Extension
Regulation Of Non-canonical Wnt Signaling Pathway
Neural Crest Cell Migration
Cell Adhesion
Cell-cell Signaling
Axon Guidance
Embryonic Pattern Specification
T Cell Costimulation
Positive Regulation Of T Cell Proliferation
Ephrin Receptor Signaling Pathway
Pathways
NRAGE signals death through JNK
Rho GTPase cycle
EPHB-mediated forward signaling
EPH-ephrin mediated repulsion of cells
G alpha (12/13) signalling events
Activated NTRK2 signals through CDK5
EPH-Ephrin signaling
EPH-Ephrin signaling
EPHB-mediated forward signaling
EPHB-mediated forward signaling
Ephrin signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells
Drugs
Diseases
Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
GWAS
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Renal sinus fat (
22044751
)
Waist circumference (
28552196
)
Interacting Genes
33 interacting genes:
ABCA1
ANK1
BTRC
CAMK2G
CD44
CDC42
CSNK1A1
EFNB1
EPHA2
FNDC3B
HRAS
MAPK8IP1
MAPK8IP2
MYC
NME1
OSBPL1A
PARD3
PPP1R9B
PPP2CA
PRKCA
PRKCB
PRKCD
PRKCE
PRKCG
PRKCZ
RAC1
RHOA
SRC
SRSF5
SYCP1
UBC
YWHAG
ZKSCAN4
18 interacting genes:
ANKRD46
CAPN10
CUL3
DNAJC5
EPHA3
EPHB1
EPHB2
GRIP1
MYC
NCK2
PICK1
PTPN13
RGS3
SDCBP
SORBS1
SRC
TIAM1
YWHAQ
Entrez ID
7074
1947
HPRD ID
02820
02072
Ensembl ID
ENSG00000156299
ENSG00000090776
Uniprot IDs
A0A2X0TW27
Q13009
P98172
PDB IDs
2D8I
3KZD
3KZE
4GVC
4GVD
4K2O
4K2P
4NXP
4NXQ
4NXR
6THG
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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