Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
TIAM1 and MAPK8IP2
Data Source:
HPRD
(in vivo)
TIAM1
MAPK8IP2
Description
TIAM Rac1 associated GEF 1
mitogen-activated protein kinase 8 interacting protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Microtubule
Plasma Membrane
Cell-cell Junction
Membrane
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ruffle Membrane
Neuronal Cell Body
Dendritic Spine
Cell-cell Contact Zone
Axonal Growth Cone
Main Axon
Synapse
Glutamatergic Synapse
Extrinsic Component Of Postsynaptic Density Membrane
Cytoplasm
Postsynaptic Density
Protein-containing Complex
Neuronal Cell Body
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Microtubule Binding
Lipid Binding
Kinase Binding
Receptor Tyrosine Kinase Binding
Amyloid-beta Binding
MAP-kinase Scaffold Activity
Structural Molecule Activity
Protein Binding
Kinesin Binding
Protein Kinase Binding
Protein-containing Complex Binding
Biological Process
Cardiac Muscle Hypertrophy
Apoptotic Process
Cell-matrix Adhesion
G Protein-coupled Receptor Signaling Pathway
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Population Proliferation
Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Epithelial To Mesenchymal Transition
Cell Migration
Rac Protein Signal Transduction
Positive Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Cellular Protein-containing Complex Assembly
Response To Cocaine
Positive Regulation Of Apoptotic Process
Positive Regulation Of JUN Kinase Activity
Ephrin Receptor Signaling Pathway
Positive Regulation Of Axonogenesis
Regulation Of Small GTPase Mediated Signal Transduction
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Dendritic Spine Morphogenesis
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of ERK1 And ERK2 Cascade
Protein Localization To Membrane
Activation Of GTPase Activity
NMDA Selective Glutamate Receptor Signaling Pathway
Positive Regulation Of Schwann Cell Chemotaxis
Regulation Of Dopaminergic Neuron Differentiation
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Neuron Projection Extension
Regulation Of Non-canonical Wnt Signaling Pathway
Behavioral Fear Response
Signal Complex Assembly
JNK Cascade
Mating Behavior
Regulation Of Signaling Receptor Activity
Positive Regulation Of Stress-activated MAPK Cascade
Social Behavior
Regulation Of JNK Cascade
Nonassociative Learning
Dendrite Morphogenesis
Regulation Of Synaptic Transmission, Glutamatergic
Excitatory Postsynaptic Potential
Regulation Of NMDA Receptor Activity
Regulation Of AMPA Receptor Activity
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
NRAGE signals death through JNK
Rho GTPase cycle
EPHB-mediated forward signaling
EPH-ephrin mediated repulsion of cells
G alpha (12/13) signalling events
Activated NTRK2 signals through CDK5
Drugs
Diseases
GWAS
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Renal sinus fat (
22044751
)
Waist circumference (
28552196
)
Gut microbiota relative abundance (Prevotella) (
33208821
)
Hip circumference (
28552196
)
Interacting Genes
33 interacting genes:
ABCA1
ANK1
BTRC
CAMK2G
CD44
CDC42
CSNK1A1
EFNB1
EPHA2
FNDC3B
HRAS
MAPK8IP1
MAPK8IP2
MYC
NME1
OSBPL1A
PARD3
PPP1R9B
PPP2CA
PRKCA
PRKCB
PRKCD
PRKCE
PRKCG
PRKCZ
RAC1
RHOA
SRC
SRSF5
SYCP1
UBC
YWHAG
ZKSCAN4
85 interacting genes:
ADRB2
AFG3L2
ANAPC10
APP
ASRGL1
BBS10
C1QTNF3
C22orf39
C8orf33
CFL1
CHN1
CRMP1
CRP
CTNNBL1
DUSP16
DUSP18
EGFR
ERBB2
ERG28
EZH2
FGF12
FGF13
FSCN1
GALNT3
GBP2
HLA-C
HOXC8
IGIP
ING4
ITSN1
KIFC2
KLC1
LEFTY2
LRP1
LRP2
LRP8
LSM8
MAGED4B
MAP2K3
MAP2K7
MAP3K10
MAP3K11
MAP3K12
MAPK10
MAPK8
MAPK8IP1
MAPK8IP3
MAPK9
MASP1
MNDA
MRE11
MSRB3
NDUFS6
NUMB
PLXNA3
POLR1H
PRSS23
RAI1
RBM4
RBX1
RPS6KB2
RYBP
SCLT1
SH2D1B
SLC39A13
SLPI
SMARCB1
SMS
SPINK2
SPSB3
SRP19
SYNE2
TARBP2
TIAM1
TMEM128
TP53BP2
UNC119
USP46
VCP
VPS33B
VRK2
YY1AP1
ZNF593
ZNF670
ZNF784
Entrez ID
7074
23542
HPRD ID
02820
09674
Ensembl ID
ENSG00000156299
ENSG00000008735
Uniprot IDs
A0A2X0TW27
Q13009
Q13387
PDB IDs
2D8I
3KZD
3KZE
4GVC
4GVD
4K2O
4K2P
4NXP
4NXQ
4NXR
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?