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TIAM1 and PPP1R9B
Data Source:
HPRD
(two hybrid, in vivo)
TIAM1
PPP1R9B
Description
TIAM Rac1 associated GEF 1
protein phosphatase 1 regulatory subunit 9B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Microtubule
Plasma Membrane
Cell-cell Junction
Membrane
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Ruffle Membrane
Neuronal Cell Body
Dendritic Spine
Cell-cell Contact Zone
Axonal Growth Cone
Main Axon
Synapse
Glutamatergic Synapse
Extrinsic Component Of Postsynaptic Density Membrane
Protein Phosphatase Type 1 Complex
Nucleoplasm
Cytoplasm
Plasma Membrane
Adherens Junction
Postsynaptic Density
Actin Cytoskeleton
Lamellipodium
Filopodium
Dendrite
Growth Cone
Cortical Actin Cytoskeleton
Ruffle Membrane
Neuronal Cell Body
Dendritic Spine Neck
Dendritic Spine Head
Cytoplasmic Side Of Dendritic Spine Plasma Membrane
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Microtubule Binding
Lipid Binding
Kinase Binding
Receptor Tyrosine Kinase Binding
Protein Kinase Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
Protein C-terminus Binding
Protein Phosphatase 1 Binding
Kinase Binding
D2 Dopamine Receptor Binding
Ion Channel Binding
Actin Filament Binding
Biological Process
Cardiac Muscle Hypertrophy
Apoptotic Process
Cell-matrix Adhesion
G Protein-coupled Receptor Signaling Pathway
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Population Proliferation
Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Epithelial To Mesenchymal Transition
Cell Migration
Rac Protein Signal Transduction
Positive Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Cellular Protein-containing Complex Assembly
Response To Cocaine
Positive Regulation Of Apoptotic Process
Positive Regulation Of JUN Kinase Activity
Ephrin Receptor Signaling Pathway
Positive Regulation Of Axonogenesis
Regulation Of Small GTPase Mediated Signal Transduction
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Dendritic Spine Morphogenesis
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of ERK1 And ERK2 Cascade
Protein Localization To Membrane
Activation Of GTPase Activity
NMDA Selective Glutamate Receptor Signaling Pathway
Positive Regulation Of Schwann Cell Chemotaxis
Regulation Of Dopaminergic Neuron Differentiation
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Neuron Projection Extension
Regulation Of Non-canonical Wnt Signaling Pathway
Regulation Of Cell Growth By Extracellular Stimulus
Regulation Of Protein Phosphorylation
Response To Amphetamine
Developmental Process Involved In Reproduction
Protein Phosphorylation
Actin Filament Organization
Cell Cycle Arrest
Regulation Of Exit From Mitosis
Aging
Learning
RNA Splicing
Dendrite Development
Cell Migration
Calcium-mediated Signaling
Hippocampus Development
Cerebral Cortex Development
Actin Filament Depolymerization
Negative Regulation Of Cell Growth
Neuron Projection Development
Negative Regulation Of Phosphoprotein Phosphatase Activity
Response To Prostaglandin E
Response To Nicotine
Cellular Response To Drug
Response To Immobilization Stress
Regulation Of Cell Population Proliferation
Filopodium Assembly
Response To Steroid Hormone
Modulation Of Chemical Synaptic Transmission
Male Mating Behavior
Reproductive System Development
Cellular Response To Morphine
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Estradiol Stimulus
Response To Clozapine
Cellular Response To Peptide
Positive Regulation Of Protein Localization To Plasma Membrane
Protein Localization To Actin Cytoskeleton
Positive Regulation Of Protein Localization To Actin Cortical Patch
Response To Kainic Acid
Response To L-phenylalanine Derivative
Protein Localization To Cell Periphery
Regulation Of Opioid Receptor Signaling Pathway
Pathways
NRAGE signals death through JNK
Rho GTPase cycle
EPHB-mediated forward signaling
EPH-ephrin mediated repulsion of cells
G alpha (12/13) signalling events
Activated NTRK2 signals through CDK5
Drugs
Diseases
GWAS
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Renal sinus fat (
22044751
)
Waist circumference (
28552196
)
Platelet distribution width (
32888494
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
33 interacting genes:
ABCA1
ANK1
BTRC
CAMK2G
CD44
CDC42
CSNK1A1
EFNB1
EPHA2
FNDC3B
HRAS
MAPK8IP1
MAPK8IP2
MYC
NME1
OSBPL1A
PARD3
PPP1R9B
PPP2CA
PRKCA
PRKCB
PRKCD
PRKCE
PRKCG
PRKCZ
RAC1
RHOA
SRC
SRSF5
SYCP1
UBC
YWHAG
ZKSCAN4
25 interacting genes:
ACTA1
ACTN2
ADRA1A
ADRA1B
ADRA2A
ADRA2B
ADRA2C
CCKAR
CCKBR
CDKN2A
CHRM3
DCX
DRD2
LRRC7
MAPK1
PPP1CA
PPP1CB
PPP1CC
PPP1R2
PPP1R9A
PRKACA
RGS2
RPS6KB1
TGOLN2
TIAM1
Entrez ID
7074
84687
HPRD ID
02820
04506
Ensembl ID
ENSG00000156299
ENSG00000108819
Uniprot IDs
A0A2X0TW27
Q13009
Q96SB3
PDB IDs
2D8I
3KZD
3KZE
4GVC
4GVD
4K2O
4K2P
4NXP
4NXQ
4NXR
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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