EFNB1 and ANKRD46

Data Source:
BioGRID (two hybrid)

		EFNB1	ANKRD46
Description		ephrin B1	ankyrin repeat domain 46
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft Synapse Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Protein Binding Ephrin Receptor Binding
	Biological Process	Neural Crest Cell Migration Cell Adhesion Cell-cell Signaling Axon Guidance Embryonic Pattern Specification T Cell Costimulation Positive Regulation Of T Cell Proliferation Ephrin Receptor Signaling Pathway
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases		Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
GWAS			Atrioventricular conduction ( 21041692) Body mass index ( 26426971) Percentage gas trapping ( 26030696)
Interacting Genes		18 interacting genes: ANKRD46 CAPN10 CUL3 DNAJC5 EPHA3 EPHB1 EPHB2 GRIP1 MYC NCK2 PICK1 PTPN13 RGS3 SDCBP SORBS1 SRC TIAM1 YWHAQ	61 interacting genes: AMIGO1 APH1A AQP6 ARL13B BIK BSCL2 C16orf54 CD22 CD46 CLDN20 CLDN7 CLEC4D CRB3 CREB3L1 CXADR CYB561 EBP EFNB1 EFNB2 ELOVL4 FAM174A FAM209A GOLM1 GPR152 GPR42 HSD17B11 HSD17B13 IFNLR1 KASH5 KIR2DL3 LAMTOR5 LDLRAD1 LRRC25 MFF MMGT1 MUC1 NCAPH2 NSG2 PLPP4 PVR RELL2 RETREG3 SCN3B SECTM1 SHISA3 SLC10A6 SLC16A2 SLC18A1 SLC39A9 ST6GALNAC6 STX1A STX2 STX4 SUSD3 THAP4 TIMMDC1 TMEM248 TMEM31 TMEM45B TMEM79 TMPRSS2
Entrez ID		1947	157567
HPRD ID		02072	14103
Ensembl ID		ENSG00000090776	ENSG00000186106
Uniprot IDs		P98172	A0A024R9E1 A0A024R9G2 B3KT99 Q86W74
PDB IDs		6THG
Enriched GO Terms of Interacting Partners?
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