NAGK and PJA1

Data Source:
BioGRID (enzymatic study)

		NAGK	PJA1
Description		N-acetylglucosamine kinase	praja ring finger ubiquitin ligase 1
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytoplasm
	Molecular Function	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Protein Ubiquitination Protein Catabolic Process
Pathways		Synthesis of UDP-N-acetyl-glucosamine	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		N-Acetylglucosamine
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)	Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		33 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82	64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440
Entrez ID		55577	64219
HPRD ID		08441	02335
Ensembl ID		ENSG00000124357	ENSG00000181191
Uniprot IDs		A0A384N6G7 C9JEV6 Q9UJ70	Q8NG27
PDB IDs		2CH5 2CH6	2L0B
Enriched GO Terms of Interacting Partners?
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