NAGK and ANKRD1

Data Source:
BioGRID (two hybrid)

		NAGK	ANKRD1
Description		N-acetylglucosamine kinase	ankyrin repeat domain 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol I Band
	Molecular Function	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity	RNA Polymerase II Transcription Factor Binding P53 Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding
	Biological Process	N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Regulation Of Lipid Metabolic Process Cellular Response To Drug Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Protein Kinase C Signaling Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of DNA Biosynthetic Process
Pathways		Synthesis of UDP-N-acetyl-glucosamine	PPARA activates gene expression
Drugs		N-Acetylglucosamine
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 29617998) Refractive error ( 32231278)
Interacting Genes		33 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82	23 interacting genes: APPL1 ARHGDIB ASH2L CASQ2 CDCA7L DNAJB6 DST DYSF LRPPRC MAPRE3 MEOX2 MYBPC1 MYL1 MYOM2 MYPN NAGK REPS1 SPANXN2 TRIM55 TRIM63 TTN TULP3 ZNF446
Entrez ID		55577	27063
HPRD ID		08441	10647
Ensembl ID		ENSG00000124357	ENSG00000148677
Uniprot IDs		A0A384N6G7 C9JEV6 Q9UJ70	A0A384NYH5 Q15327
PDB IDs		2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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