PJA1 and TMEM214

Data Source:
BioGRID (enzymatic study)

		PJA1	TMEM214
Description		praja ring finger ubiquitin ligase 1	transmembrane protein 214
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cytoplasmic Microtubule Integral Component Of Membrane
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Apoptotic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440	2 interacting genes: LSM1 PJA1
Entrez ID		64219	54867
HPRD ID		02335	07887
Ensembl ID		ENSG00000181191	ENSG00000119777
Uniprot IDs		Q8NG27	Q6NUQ4
PDB IDs		2L0B
Enriched GO Terms of Interacting Partners?
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