PJA1 and COASY

Data Source:
BioGRID (enzymatic study)

		PJA1	COASY
Description		praja ring finger ubiquitin ligase 1	Coenzyme A synthase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Coenzyme A Biosynthetic Process Phosphorylation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Coenzyme A biosynthesis
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)	Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552)
Interacting Genes		64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440	11 interacting genes: APP BTK CNTROB KIAA1958 KRT20 LYN PJA1 RPS6KB1 RPS6KB2 SRC SYK
Entrez ID		64219	80347
HPRD ID		02335	13080
Ensembl ID		ENSG00000181191	ENSG00000068120
Uniprot IDs		Q8NG27	Q13057
PDB IDs		2L0B
Enriched GO Terms of Interacting Partners?
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