PHYH and PATJ

Data Source:
BioGRID (two hybrid)

		PHYH	PATJ
Description		phytanoyl-CoA 2-hydroxylase	PATJ crumbs cell polarity complex component
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol 9+0 Non-motile Cilium	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Ferrous Iron Binding Carboxylic Acid Binding L-ascorbic Acid Binding Phytanoyl-CoA Dioxygenase Activity	Protein Binding
	Biological Process	Fatty Acid Alpha-oxidation 2-oxoglutarate Metabolic Process Protein Targeting To Peroxisome Isoprenoid Metabolic Process 2-oxobutyrate Catabolic Process Methyl-branched Fatty Acid Metabolic Process	Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Bicellular Tight Junction Assembly Tight Junction Assembly
Pathways		Alpha-oxidation of phytanate Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Drugs		Antihemophilic factor, human recombinant Ascorbic acid Lonoctocog alfa Moroctocog alfa
Diseases		Refsum disease; Heredopathia atactica polyneuritiformis
GWAS			3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)
Interacting Genes		11 interacting genes: ACSL6 APP F8 FAM9B FKBP4 MAGEA11 PATJ PEX7 PHYHIP SIRPA TOM1L1	35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3
Entrez ID		5264	10207
HPRD ID		03609	04434
Ensembl ID		ENSG00000107537	ENSG00000132849
Uniprot IDs		O14832
PDB IDs		2A1X
Enriched GO Terms of Interacting Partners?
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