RBMX and SREK1

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		RBMX	SREK1
Description		RNA binding motif protein X-linked	splicing regulatory glutamic acid and lysine rich protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Euchromatin Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Membrane Protein-containing Complex Supraspliceosomal Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription By RNA Polymerase II MRNA Splice Site Selection Membrane Protein Ectodomain Proteolysis RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Homooligomerization Cellular Response To Interleukin-1	MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Pediatric autoimmune diseases ( 26301688)	Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)
Interacting Genes		46 interacting genes: APOBEC3C CCDC33 CIRBP CLK1 CLK3 CMTM6 CNNM3 CSNK2A1 FUS FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS1 KHDRBS2 KHDRBS3 LNX1 MAGOHB MYPOP NABP1 NFE2L2 NYX PCDHB14 PRPF31 PRR3 PSMF1 RAMAC RBM3 RBM7 RBMY1A1 RBMY1E RBMY1F RBMY1J ROBO3 SNRPA SOCS3 SORBS3 SREK1 SRPK2 SRSF3 SRSF9 STAT5A TRA2B XRN1 ZNF490	60 interacting genes: ARL6IP4 CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 PRPF40A RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2
Entrez ID		27316	140890
HPRD ID		02186	18043
Ensembl ID		ENSG00000147274	ENSG00000153914
Uniprot IDs		P38159	Q8WXA9
PDB IDs		2MB0 2MKS
Enriched GO Terms of Interacting Partners?
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