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RBMX and NFE2L2
Data Source:
BioGRID
(two hybrid)
RBMX
NFE2L2
Description
RNA binding motif protein X-linked
nuclear factor, erythroid 2 like 2
Image
GO Annotations
Cellular Component
Euchromatin
Extracellular Space
Nucleus
Nucleoplasm
Spliceosomal Complex
Membrane
Protein-containing Complex
Supraspliceosomal Complex
Extracellular Exosome
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Centrosome
Cytosol
Plasma Membrane
Protein-DNA Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Chromatin Binding
RNA Binding
Single-stranded RNA Binding
MRNA Binding
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Activating Transcription Factor Binding
Transcription Coregulator Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Domain Specific Binding
Sequence-specific DNA Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
Transcription By RNA Polymerase II
MRNA Splice Site Selection
Membrane Protein Ectodomain Proteolysis
RNA Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of MRNA Splicing, Via Spliceosome
Positive Regulation Of MRNA Splicing, Via Spliceosome
Protein Homooligomerization
Cellular Response To Interleukin-1
Regulation Of Transcription By RNA Polymerase II
Inflammatory Response
Aging
Response To Lithium Ion
Proteasomal Ubiquitin-independent Protein Catabolic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Neuron Projection Development
Viral Process
Protein Ubiquitination
Positive Regulation Of Blood Coagulation
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Oxidative Stress
Cellular Response To Drug
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
PERK-mediated Unfolded Protein Response
Cellular Response To Glucose Starvation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Cell Redox Homeostasis
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Aflatoxin Catabolic Process
Positive Regulation Of Glucose Import
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Hydrogen Peroxide
Cellular Response To Copper Ion
Cellular Response To Tumor Necrosis Factor
Cellular Response To Fluid Shear Stress
Cellular Response To Laminar Fluid Shear Stress
Negative Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Positive Regulation Of Glutathione Biosynthetic Process
Cellular Response To Angiotensin
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Regulation Of Removal Of Superoxide Radicals
Negative Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS
Pediatric autoimmune diseases (
26301688
)
Estimated glomerular filtration rate (
31152163
31451708
30604766
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
HDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
Interacting Genes
46 interacting genes:
APOBEC3C
CCDC33
CIRBP
CLK1
CLK3
CMTM6
CNNM3
CSNK2A1
FUS
FXR2
HNRNPK
IL7R
ITSN2
JAK2
KHDRBS1
KHDRBS2
KHDRBS3
LNX1
MAGOHB
MYPOP
NABP1
NFE2L2
NYX
PCDHB14
PRPF31
PRR3
PSMF1
RAMAC
RBM3
RBM7
RBMY1A1
RBMY1E
RBMY1F
RBMY1J
ROBO3
SNRPA
SOCS3
SORBS3
SREK1
SRPK2
SRSF3
SRSF9
STAT5A
TRA2B
XRN1
ZNF490
37 interacting genes:
ATF4
BPTF
CASP1
CASP3
CDH1
CHD6
COPS7A
CREB3
CREBBP
DCAF11
EIF2AK3
GSK3B
JUN
JUND
KDM1A
KEAP1
KPNA3
MAFF
MAFG
MAFK
MAPK7
MAPK8
NCOR2
NFE2
NFE2L3
PAQR4
PMF1
PPARG
PRKCA
PRKCD
RBMX
SUMO1
SUMO2
TNNT1
TRIM24
UBE2E2
WAC
Entrez ID
27316
4780
HPRD ID
02186
02732
Ensembl ID
ENSG00000147274
ENSG00000116044
Uniprot IDs
P38159
Q16236
PDB IDs
2MB0
2MKS
2FLU
2LZ1
3ZGC
4IFL
5WFV
6T7V
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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