RBMX and SORBS3

Data Source:
HPRD (two hybrid)

		RBMX	SORBS3
Description		RNA binding motif protein X-linked	sorbin and SH3 domain containing 3
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GO Annotations	Cellular Component	Euchromatin Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Membrane Protein-containing Complex Supraspliceosomal Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription By RNA Polymerase II MRNA Splice Site Selection Membrane Protein Ectodomain Proteolysis RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Homooligomerization Cellular Response To Interleukin-1	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Smooth Muscle Contraction
Drugs
Diseases
GWAS		Pediatric autoimmune diseases ( 26301688)	Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		46 interacting genes: APOBEC3C CCDC33 CIRBP CLK1 CLK3 CMTM6 CNNM3 CSNK2A1 FUS FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS1 KHDRBS2 KHDRBS3 LNX1 MAGOHB MYPOP NABP1 NFE2L2 NYX PCDHB14 PRPF31 PRR3 PSMF1 RAMAC RBM3 RBM7 RBMY1A1 RBMY1E RBMY1F RBMY1J ROBO3 SNRPA SOCS3 SORBS3 SREK1 SRPK2 SRSF3 SRSF9 STAT5A TRA2B XRN1 ZNF490	133 interacting genes: ABI2 ABL1 ADAM15 ADAMTSL4 ADAT3 AKIRIN2 AKT2 ANKS1A ARNT2 C1orf109 CATSPER1 CBFA2T2 CBLB CCDC102B CCDC120 CCDC187 CCDC57 CCDC6 CCHCR1 CCNH CCNL1 CDC23 CDKN2C CFAP206 CHERP COG4 CPEB2 CPNE1 CPNE2 CPNE8 CPSF7 CRACR2A DDX17 DDX6 DIP2A DLG5 DMRTB1 DVL2 DVL3 EFHC1 EFS EIF3H ENKD1 FAM214B FAM53C FASLG FBXL19 FLOT1 FNDC11 GAS8 GEM GLRA1 GPANK1 GPKOW GYS1 HGS HNRNPF HNRNPK HNRNPUL1 IMP3 INPPL1 INSC IQUB KANK2 KIAA0408 KIAA1217 KIFC3 MAPK1 MAPK3 MKRN3 MYO15B NAB2 NAF1 NCK1 NCKIPSD NEK6 NFKBID NHSL2 NOTCH3 NRBP1 OIP5 OSGIN1 PAK2 PAK5 PHETA1 PHF1 PIBF1 PLEKHN1 PLOD3 PNMA5 POLE2 POLR1C PPFIA3 PPIL6 PPP1R18 QARS1 RAD51D RBMX RIN1 ROPN1 RUNX1T1 SAFB2 SAXO1 SCNM1 SETD5 SH2D4A SOCS7 SPG21 SRCIN1 SYNPO2L TBC1D22B TCEANC TEAD4 TEPSIN TNS2 TRIM23 TRIM27 TRIM41 TSGA10 TSGA10IP TXLNA USP2 VARS2 VCL VPS37B VPS37C WIPF2 ZBED1 ZBTB25 ZBTB7B ZC2HC1C ZC4H2 ZNF414
Entrez ID		27316	10174
HPRD ID		02186	11535
Ensembl ID		ENSG00000147274	ENSG00000120896
Uniprot IDs		P38159	O60504
PDB IDs		2MB0 2MKS	2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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