SREK1 and SRSF10

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SREK1	SRSF10
Description		splicing regulatory glutamic acid and lysine rich protein 1	serine and arginine rich splicing factor 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding RS Domain Binding Unfolded Protein Binding
	Biological Process	MRNA Processing RNA Splicing	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated MRNA Splice Site Selection Cytosolic Transport Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)	Chronotype ( 30696823) Obesity-related traits ( 23251661)
Interacting Genes		60 interacting genes: ARL6IP4 CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 PRPF40A RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2	18 interacting genes: CLK1 CLK3 CSNK2A1 DAPK1 FBXO7 FUS MPP1 PTPN11 RNPS1 SNRNP70 SREK1 SRSF1 SRSF4 SYCE1L TRA2A TRA2B YWHAB YWHAG
Entrez ID		140890	10772
HPRD ID		18043	05562
Ensembl ID		ENSG00000153914	ENSG00000188529
Uniprot IDs		Q8WXA9	A0A0S2Z504 B3KNY6 O75494 Q5JRI1
PDB IDs
Enriched GO Terms of Interacting Partners?
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