LARP1 and TNNT1

Data Source:
BioGRID (two hybrid)

		LARP1	TNNT1
Description		La ribonucleoprotein 1, translational regulator	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Polysome Cytoplasmic Stress Granule Membrane TORC1 Complex Polysomal Ribosome	Cytosol Troponin Complex
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Ribosomal Small Subunit Binding Cadherin Binding MRNA 5'-UTR Binding	Protein Binding Tropomyosin Binding Troponin T Binding
	Biological Process	Translational Initiation Cell Population Proliferation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Macroautophagy Negative Regulation Of Translation TOR Signaling TORC1 Signaling Positive Regulation Of Viral Genome Replication Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation MRNA Stabilization Cellular Response To Rapamycin Response To Amino Acid Starvation	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction
Pathways			Striated Muscle Contraction
Drugs
Diseases			Nemaline myopathy
GWAS		Chin dimples ( 27182965) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Monobrow ( 27182965) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Height ( 31562340)
Interacting Genes		9 interacting genes: BCL2L1 CSNK2A1 KASH5 SRPK1 TNNT1 YWHAB YWHAG YWHAQ YWHAZ	69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		23367	7138
HPRD ID		11225	01841
Ensembl ID		ENSG00000155506	ENSG00000105048
Uniprot IDs		Q6PKG0	P13805
PDB IDs		4ZC4 5C0V 5V4R 5V7C 5V87 6PW3
Enriched GO Terms of Interacting Partners?
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