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DVL3 and PRPF31
Data Source:
BioGRID
(two hybrid)
DVL3
PRPF31
Description
dishevelled segment polarity protein 3
pre-mRNA processing factor 31
Image
GO Annotations
Cellular Component
Chromatin
Cytosol
Nucleus
Nucleoplasm
U2-type Spliceosomal Complex
U4 SnRNP
U4atac SnRNP
Cajal Body
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
U2-type Precatalytic Spliceosome
Precatalytic Spliceosome
MLL1 Complex
Spliceosomal Tri-snRNP Complex
Molecular Function
Protease Binding
Signaling Receptor Binding
Frizzled Binding
Protein Binding
Beta-catenin Binding
Small GTPase Binding
RNA Binding
Protein Binding
U4 SnRNA Binding
U4atac SnRNA Binding
Identical Protein Binding
Ribonucleoprotein Complex Binding
SnRNP Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Response To Drug
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Protein Stabilization
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Regulation Of Cellular Protein Localization
Beta-catenin Destruction Complex Disassembly
Spliceosomal Tri-snRNP Complex Assembly
MRNA Splicing, Via Spliceosome
SnoRNA Localization
Ribonucleoprotein Complex Localization
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
mRNA Splicing - Major Pathway
Drugs
Diseases
Retinitis pigmentosa (RP)
GWAS
Facial morphology traits (63 three-dimensional facial segments) (
29459680
)
Major depressive disorder (
22472876
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Change in HbA1c levels in response to metformin treatment in type 2 diabetes (
29650774
)
Interacting Genes
164 interacting genes:
ABT1
ADAP1
AKAP17A
ANKRD36B
AP3M1
AXIN1
BAHD1
BEND7
BHLHE40
C1orf35
C8orf33
CBX8
CCDC33
CCNK
CCNL1
CDYL2
CEP57L1
CEP70
CEP76
CLK1
CSNK1D
CSNK1E
CSNK2A1
CT45A10
CT45A3
CTNNB1
CYSRT1
DAB2
DDX54
DIDO1
DPPA2
DVL1
EIF1B
EIF3D
ENKD1
FAM13C
FAM90A1
FARS2
FGF16
FLACC1
GADD45GIP1
HOMER3
HOXA5
HOXC5
HOXC8
INO80B
KAT7
KAZN
KCTD10
KCTD7
KLF1
KLF15
KLF3
KLF4
KLHL12
LENG8
LNX1
LONRF1
LRRK2
LUZP4
LY6H
MAB21L3
MAGEB4
MAGOHB
MARK2
MATN2
NFYA
NKD1
NOL12
NXF1
PATZ1
PHF19
PIK3CB
PITX1
PLAGL2
PLN
PNKP
PPM1A
PPP1R16B
PPP2CA
PRKAA2
PRPF18
PRPF3
PRPF31
PRPF38A
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSME3
PSMF1
RBM15B
RBM39
RNF151
RPL11
RPS10
RRP8
RWDD2B
SAP30L
SHFL
SNIP1
SNX22
SORBS3
STOM
SUV39H1
SYT6
SYTL4
TBPL1
TCEA2
TCEANC
TFG
THAP7
TLE5
TNFAIP8L1
TNP1
TPTEP2-CSNK1E
TRAF2
TRIM41
TRIM54
TSN
TSPYL1
TSPYL6
UTP3
VANGL1
VAX1
WDR25
WT1
XPA
YTHDC1
ZBTB24
ZBTB26
ZBTB47
ZBTB48
ZBTB8A
ZFP57
ZNF165
ZNF2
ZNF264
ZNF319
ZNF408
ZNF417
ZNF441
ZNF444
ZNF497
ZNF512B
ZNF552
ZNF581
ZNF648
ZNF696
ZNF697
ZNF699
ZNF71
ZNF764
ZNF774
ZNF775
ZNF792
ZNF821
ZNF837
ZRSR2
ZSCAN21
ZSCAN22
ZSCAN25
135 interacting genes:
ASB15
BHLHB9
BICD2
C1QTNF1
CALCOCO2
CAPNS2
CARD14
CBY2
CCDC106
CCDC136
CCDC33
CCDC57
CCDC70
CCNDBP1
CDC23
CDCA7L
CDR2L
CEP70
CYSRT1
DVL2
DVL3
EFEMP2
EVI5
FANCA
FANCC
FASTK
FLACC1
FSD2
FXR1
GOLGA2
GOLGA6L9
HAP1
HES7
HNRNPH2
HNRNPK
HOOK2
HSF2BP
JAKMIP2
KANK2
KCTD6
KHDRBS2
KHDRBS3
KIFC3
KRT15
KRT31
KRT34
KRT35
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-8
KRTAP10-9
KRTAP19-5
KRTAP4-11
KRTAP6-3
LBX1
LDOC1
LHX8
LURAP1
LZTS2
MDFI
MEIS3
MEOX2
MID2
MIPOL1
MKRN3
MTUS2
NCAPH2
NCKIPSD
NOTCH2NLA
PAK5
PDE4DIP
PHC2
PHF5A
PICK1
PLEKHG4
PNMA1
PNMA2
PNMA3
PPIH
PPP1R16A
PPP2R3C
PRDM14
PRICKLE1
PRPF3
PSTPIP1
RACK1
RBAK
RBM25
RBM4
RBMX
RBMY1A1
RBMY1F
RBMY1J
REL
RINT1
RUNDC3A
SIAH1
SLAIN1
SNRNP200
SRSF3
SSX2IP
STX11
TADA2A
TFIP11
TLE5
TMCC2
TP53BP2
TRIM14
TRIM23
TRIM27
TRIM41
TSGA10
UBXN11
USH1G
USP15
VWC2
ZFP64
ZFP69B
ZNF24
ZNF250
ZNF408
ZNF417
ZNF473
ZNF48
ZNF587
ZNF668
ZNF71
ZNF774
ZNF792
ZNF837
ZRANB1
ZSCAN22
Entrez ID
1857
26121
HPRD ID
03222
05917
Ensembl ID
ENSG00000161202
ENSG00000105618
Uniprot IDs
Q92997
Q9UG07
Q8WWY3
PDB IDs
6V7O
2OZB
3JCR
3SIU
3SIV
5O9Z
6AH0
6AHD
6QW6
6QX9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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