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DVL3 and STOM
Data Source:
BioGRID
(two hybrid)
DVL3
STOM
Description
dishevelled segment polarity protein 3
stomatin
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Cytosol
Extracellular Space
Mitochondrion
Endoplasmic Reticulum
Cytoskeleton
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Vesicle
Azurophil Granule Membrane
Specific Granule Membrane
Melanosome
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Tertiary Granule Membrane
Blood Microparticle
Molecular Function
Protease Binding
Signaling Receptor Binding
Frizzled Binding
Protein Binding
Beta-catenin Binding
Small GTPase Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
RNA Polymerase Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Response To Drug
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Protein Stabilization
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Regulation Of Cellular Protein Localization
Beta-catenin Destruction Complex Disassembly
Neutrophil Degranulation
Positive Regulation By Host Of Viral Genome Replication
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Acid-sensing Ion Channel Activity
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Stimuli-sensing channels
Neutrophil degranulation
Drugs
Diseases
Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS
Facial morphology traits (63 three-dimensional facial segments) (
29459680
)
Major depressive disorder (
22472876
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Interacting Genes
164 interacting genes:
ABT1
ADAP1
AKAP17A
ANKRD36B
AP3M1
AXIN1
BAHD1
BEND7
BHLHE40
C1orf35
C8orf33
CBX8
CCDC33
CCNK
CCNL1
CDYL2
CEP57L1
CEP70
CEP76
CLK1
CSNK1D
CSNK1E
CSNK2A1
CT45A10
CT45A3
CTNNB1
CYSRT1
DAB2
DDX54
DIDO1
DPPA2
DVL1
EIF1B
EIF3D
ENKD1
FAM13C
FAM90A1
FARS2
FGF16
FLACC1
GADD45GIP1
HOMER3
HOXA5
HOXC5
HOXC8
INO80B
KAT7
KAZN
KCTD10
KCTD7
KLF1
KLF15
KLF3
KLF4
KLHL12
LENG8
LNX1
LONRF1
LRRK2
LUZP4
LY6H
MAB21L3
MAGEB4
MAGOHB
MARK2
MATN2
NFYA
NKD1
NOL12
NXF1
PATZ1
PHF19
PIK3CB
PITX1
PLAGL2
PLN
PNKP
PPM1A
PPP1R16B
PPP2CA
PRKAA2
PRPF18
PRPF3
PRPF31
PRPF38A
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSME3
PSMF1
RBM15B
RBM39
RNF151
RPL11
RPS10
RRP8
RWDD2B
SAP30L
SHFL
SNIP1
SNX22
SORBS3
STOM
SUV39H1
SYT6
SYTL4
TBPL1
TCEA2
TCEANC
TFG
THAP7
TLE5
TNFAIP8L1
TNP1
TPTEP2-CSNK1E
TRAF2
TRIM41
TRIM54
TSN
TSPYL1
TSPYL6
UTP3
VANGL1
VAX1
WDR25
WT1
XPA
YTHDC1
ZBTB24
ZBTB26
ZBTB47
ZBTB48
ZBTB8A
ZFP57
ZNF165
ZNF2
ZNF264
ZNF319
ZNF408
ZNF417
ZNF441
ZNF444
ZNF497
ZNF512B
ZNF552
ZNF581
ZNF648
ZNF696
ZNF697
ZNF699
ZNF71
ZNF764
ZNF774
ZNF775
ZNF792
ZNF821
ZNF837
ZRSR2
ZSCAN21
ZSCAN22
ZSCAN25
81 interacting genes:
AIG1
APOA2
ASIC1
ASIC2
ASIC3
ATP1B3
ATP6V0B
ATP6V0C
BCL2L2
BNIP1
C2
C3orf52
CFHR5
CHST1
CLDN19
CLRN2
CMTM5
CNIH3
CTXN3
CYB5B
CYB5R3
DAGLA
DVL3
EMP1
ERG28
FAXDC2
FUNDC2
GIMAP1
GIMAP5
GPR25
GPR37L1
GRM2
HMOX2
KCNK1
KTN1
LANCL1
LNPEP
MGLL
MMP14
NKG7
ORMDL1
PEDS1-UBE2V1
PEMT
PGA4
PMP22
PTCH1
RPL13A
RPRM
RTP2
RUVBL1
RUVBL2
SCD
SELENOK
SERP2
SFT2D1
SFT2D2
SFXN1
SFXN5
SLC2A1
SLC35B4
SMCO4
STX6
TECR
THSD7B
TMEM109
TMEM120B
TMEM140
TMEM14B
TMEM203
TMEM208
TMEM254
TMEM60
TMEM86B
TMEM98
TMPO
TNF
TNFRSF10C
TSPO2
VAMP4
WFDC2
YIPF6
Entrez ID
1857
2040
HPRD ID
03222
00585
Ensembl ID
ENSG00000161202
ENSG00000148175
Uniprot IDs
Q92997
Q9UG07
A0A024R882
F8VSL7
P27105
PDB IDs
6V7O
Enriched GO Terms of Interacting Partners
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