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DVL3 and TCEA2
Data Source:
BioGRID
(two hybrid)
DVL3
TCEA2
Description
dishevelled segment polarity protein 3
transcription elongation factor A2
Image
GO Annotations
Cellular Component
Chromatin
Cytosol
Nucleoplasm
Centrosome
Transcription Elongation Factor Complex
Molecular Function
Protease Binding
Signaling Receptor Binding
Frizzled Binding
Protein Binding
Beta-catenin Binding
Small GTPase Binding
DNA Binding
Protein Binding
Zinc Ion Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Response To Drug
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Protein Stabilization
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Regulation Of Cellular Protein Localization
Beta-catenin Destruction Complex Disassembly
DNA-templated Transcription, Elongation
Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Facial morphology traits (63 three-dimensional facial segments) (
29459680
)
Major depressive disorder (
22472876
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Adult body size (
32376654
)
Adventurousness (
30643258
)
Anxiety (
31906708
)
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Eosinophil counts (
32888494
)
Low density lipoprotein cholesterol levels (
32154731
)
Pulse pressure (
27841878
30578418
)
Serum thyroid-stimulating hormone levels (
25436638
)
Systolic blood pressure (
27841878
)
Triglyceride levels (
29083408
)
Type 2 diabetes (adjusted for BMI) (
30297969
)
Interacting Genes
164 interacting genes:
ABT1
ADAP1
AKAP17A
ANKRD36B
AP3M1
AXIN1
BAHD1
BEND7
BHLHE40
C1orf35
C8orf33
CBX8
CCDC33
CCNK
CCNL1
CDYL2
CEP57L1
CEP70
CEP76
CLK1
CSNK1D
CSNK1E
CSNK2A1
CT45A10
CT45A3
CTNNB1
CYSRT1
DAB2
DDX54
DIDO1
DPPA2
DVL1
EIF1B
EIF3D
ENKD1
FAM13C
FAM90A1
FARS2
FGF16
FLACC1
GADD45GIP1
HOMER3
HOXA5
HOXC5
HOXC8
INO80B
KAT7
KAZN
KCTD10
KCTD7
KLF1
KLF15
KLF3
KLF4
KLHL12
LENG8
LNX1
LONRF1
LRRK2
LUZP4
LY6H
MAB21L3
MAGEB4
MAGOHB
MARK2
MATN2
NFYA
NKD1
NOL12
NXF1
PATZ1
PHF19
PIK3CB
PITX1
PLAGL2
PLN
PNKP
PPM1A
PPP1R16B
PPP2CA
PRKAA2
PRPF18
PRPF3
PRPF31
PRPF38A
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSME3
PSMF1
RBM15B
RBM39
RNF151
RPL11
RPS10
RRP8
RWDD2B
SAP30L
SHFL
SNIP1
SNX22
SORBS3
STOM
SUV39H1
SYT6
SYTL4
TBPL1
TCEA2
TCEANC
TFG
THAP7
TLE5
TNFAIP8L1
TNP1
TPTEP2-CSNK1E
TRAF2
TRIM41
TRIM54
TSN
TSPYL1
TSPYL6
UTP3
VANGL1
VAX1
WDR25
WT1
XPA
YTHDC1
ZBTB24
ZBTB26
ZBTB47
ZBTB48
ZBTB8A
ZFP57
ZNF165
ZNF2
ZNF264
ZNF319
ZNF408
ZNF417
ZNF441
ZNF444
ZNF497
ZNF512B
ZNF552
ZNF581
ZNF648
ZNF696
ZNF697
ZNF699
ZNF71
ZNF764
ZNF774
ZNF775
ZNF792
ZNF821
ZNF837
ZRSR2
ZSCAN21
ZSCAN22
ZSCAN25
133 interacting genes:
ADAMTSL4
AGR2
AGTRAP
AKT1S1
ALAS1
AMOTL2
APP
ARMC10
AXIN2
BACH2
BHLHB9
BICD2
BOLL
BRCA1
BTBD6
CAMKV
CBY2
CCDC136
CCDC157
CCSER2
CDK11B
CENPT
CEP44
CEP76
CMTM4
CMTM6
CNTROB
COX20
CYSRT1
DAB1
DCAF10
DES
DHRS2
DNAJB9
DVL3
EAF1
EAF2
ERBB3
EXOSC8
FADD
FAM9B
FBF1
FCHO1
FXR1
GAS8
GIGYF1
GOLGA2
GPKOW
GRIPAP1
GTF2B
HES7
HIGD1C
HIP1
HMBOX1
HOMEZ
HSF2BP
IKZF1
IKZF4
KCNF1
KCTD10
KCTD7
KIAA1958
KRT40
KRTAP10-7
KRTAP10-8
KRTAP12-2
KRTAP12-3
KRTAP5-9
KXD1
LIMS1
LMNA
LRRK2
LZTS1
LZTS2
MAGEA11
MARK3
MCC
MCM2
MDK
MEOX2
MID2
MKRN3
MSANTD4
MTUS2
NAB2
NECAB1
NECAB2
OSBPL3
PIBF1
PICK1
PIH1D2
PNMA1
PNMA5
POU6F2
PRPH
RBPMS
RETREG3
RPA1
SCYL1
SH3GL2
SSC5D
STAC3
STX11
SYNE4
TARBP2
TAX1BP1
TAX1BP3
TBC1D1
TCF4
TEPSIN
TFCP2
THAP1
TMEM71
TNIP1
TOX2
TRAF1
TRAF2
TRIM23
TRIM27
TRIM38
TRIM41
TRIM54
TSGA10
USP54
VIM
WDR47
ZBTB22
ZBTB43
ZBTB8A
ZBTB9
ZKSCAN8
ZNF526
ZRANB1
Entrez ID
1857
6919
HPRD ID
03222
16069
Ensembl ID
ENSG00000161202
ENSG00000171703
Uniprot IDs
Q92997
Q9UG07
Q15560
Q6IB64
PDB IDs
6V7O
2LW4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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