PRPF31 and LBX1

Data Source:
BioGRID (two hybrid)

		PRPF31	LBX1
Description		pre-mRNA processing factor 31	ladybird homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome MLL1 Complex Spliceosomal Tri-snRNP Complex	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	RNA Binding Protein Binding U4 SnRNA Binding U4atac SnRNA Binding Identical Protein Binding Ribonucleoprotein Complex Binding SnRNP Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome SnoRNA Localization Ribonucleoprotein Complex Localization	Heart Looping Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Negative Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Spinal Cord Motor Neuron Differentiation Negative Regulation Of Neuron Differentiation Neuron Fate Determination
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Change in HbA1c levels in response to metformin treatment in type 2 diabetes ( 29650774)	Adolescent idiopathic scoliosis ( 31417091 26211971 30395268) Metabolite levels ( 23823483) Refractive error ( 32231278) Scoliosis ( 22019779)
Interacting Genes		135 interacting genes: ASB15 BHLHB9 BICD2 C1QTNF1 CALCOCO2 CAPNS2 CARD14 CBY2 CCDC106 CCDC136 CCDC33 CCDC57 CCDC70 CCNDBP1 CDC23 CDCA7L CDR2L CEP70 CYSRT1 DVL2 DVL3 EFEMP2 EVI5 FANCA FANCC FASTK FLACC1 FSD2 FXR1 GOLGA2 GOLGA6L9 HAP1 HES7 HNRNPH2 HNRNPK HOOK2 HSF2BP JAKMIP2 KANK2 KCTD6 KHDRBS2 KHDRBS3 KIFC3 KRT15 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP19-5 KRTAP4-11 KRTAP6-3 LBX1 LDOC1 LHX8 LURAP1 LZTS2 MDFI MEIS3 MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NCAPH2 NCKIPSD NOTCH2NLA PAK5 PDE4DIP PHC2 PHF5A PICK1 PLEKHG4 PNMA1 PNMA2 PNMA3 PPIH PPP1R16A PPP2R3C PRDM14 PRICKLE1 PRPF3 PSTPIP1 RACK1 RBAK RBM25 RBM4 RBMX RBMY1A1 RBMY1F RBMY1J REL RINT1 RUNDC3A SIAH1 SLAIN1 SNRNP200 SRSF3 SSX2IP STX11 TADA2A TFIP11 TLE5 TMCC2 TP53BP2 TRIM14 TRIM23 TRIM27 TRIM41 TSGA10 UBXN11 USH1G USP15 VWC2 ZFP64 ZFP69B ZNF24 ZNF250 ZNF408 ZNF417 ZNF473 ZNF48 ZNF587 ZNF668 ZNF71 ZNF774 ZNF792 ZNF837 ZRANB1 ZSCAN22	23 interacting genes: AIPL1 DES EFEMP2 EIF5A FAM221B FAM9B IQGAP1 KANK2 KIF5B KIFC3 KRTAP5-6 KRTAP9-2 MAB21L3 PHF1 PRPF31 QRICH1 RBL2 TBCEL TMEM252 TSSK3 UBTFL1 WNK3 ZNF483
Entrez ID		26121	10660
HPRD ID		05917	09178
Ensembl ID		ENSG00000105618	ENSG00000138136
Uniprot IDs		Q8WWY3	P52954
PDB IDs		2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?