CLNK and PPP1R7

Data Source:
BioGRID (two hybrid)

		CLNK	PPP1R7
Description		cytokine dependent hematopoietic cell linker	protein phosphatase 1 regulatory subunit 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Protein-containing Complex Mast Cell Granule	Nucleus Chromosome Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding Protein Phosphatase Regulator Activity Enzyme Regulator Activity
	Biological Process	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation	Positive Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX	12 interacting genes: CLNK FER HGS MAPK6 MYH3 PPP1CA PPP1CB PPP1CC SPRED1 TAB1 TNFRSF6B USHBP1
Entrez ID		116449	5510
HPRD ID		14720	04192
Ensembl ID		ENSG00000109684	ENSG00000115685
Uniprot IDs		Q7Z7G1	A0A140VK83 Q15435
PDB IDs			6HKW 6MKY 6OBN 6OBP
Enriched GO Terms of Interacting Partners?
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