CLNK and RPAIN

Data Source:
BioGRID (two hybrid)

		CLNK	RPAIN
Description		cytokine dependent hematopoietic cell linker	RPA interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Protein-containing Complex Mast Cell Granule	Fibrillar Center Nucleus Nucleoplasm Cytoplasm PML Body
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation	DNA-dependent DNA Replication DNA Repair DNA Recombination Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)	Body mass index ( 29273807) Menopause (age at onset) ( 26414677) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX	7 interacting genes: ADH6 CDCA5 CLNK CYP17A1 GSTA1 RAD51B TNS4
Entrez ID		116449	84268
HPRD ID		14720	14615
Ensembl ID		ENSG00000109684	ENSG00000129197
Uniprot IDs		Q7Z7G1	B3KTT3 Q86UA6
PDB IDs
Enriched GO Terms of Interacting Partners?
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