CLNK and FAM217A

Data Source:
BioGRID (two hybrid)

		CLNK	FAM217A
Description		cytokine dependent hematopoietic cell linker	family with sequence similarity 217 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Protein-containing Complex Mast Cell Granule
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)	Night sleep phenotypes ( 27126917)
Interacting Genes		29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX	2 interacting genes: CLNK TEX11
Entrez ID		116449	222826
HPRD ID		14720	10789
Ensembl ID		ENSG00000109684	ENSG00000145975
Uniprot IDs		Q7Z7G1	A0A024QZY6 Q8IXS0
PDB IDs
Enriched GO Terms of Interacting Partners?
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