CLNK and ANKRD50

Data Source:
BioGRID (two hybrid)

		CLNK	ANKRD50
Description		cytokine dependent hematopoietic cell linker	ankyrin repeat domain 50
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Protein-containing Complex Mast Cell Granule	Endosome
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation	Protein Transport Retrograde Transport, Endosome To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)	Cerebrospinal fluid AB1-42 levels ( 26252872) Gastric cancer ( 31383772) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Metabolite levels ( 23823483) Small vessel stroke ( 29123153)
Interacting Genes		29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX	8 interacting genes: ANKRD28 APP CLNK HIF1AN PEX5 SMURF1 ZDHHC17 ZNF250
Entrez ID		116449	57182
HPRD ID		14720	13843
Ensembl ID		ENSG00000109684	ENSG00000151458
Uniprot IDs		Q7Z7G1	Q8TB46 Q9ULJ7
PDB IDs
Enriched GO Terms of Interacting Partners?
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