CLNK and COQ9

Data Source:
BioGRID (two hybrid)

		CLNK	COQ9
Description		cytokine dependent hematopoietic cell linker	coenzyme Q9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Protein-containing Complex Mast Cell Granule	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding Lipid Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Natural Killer Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction Mast Cell Degranulation	Mitochondrial Electron Transport, NADH To Ubiquinone Ubiquinone Biosynthetic Process
Pathways			Ubiquinol biosynthesis
Drugs
Diseases			Coenzyme Q10 deficiency
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33536424 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		29 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX	33 interacting genes: ACSF2 ACTL6B ADIPOQ ALDH18A1 ANO8 BMP10 CCL4L2 CLNK COQ4 COQ8A CTSA CTXN3 CYB561D2 CYBC1 EHHADH GALNT2 HMOX1 KIR2DL3 MGLL ORMDL1 PLSCR2 SCARF1 SLC13A1 STX3 TEX264 TMEM14C TMEM79 TMEM86A TNFRSF10C TRAF3IP3 TSPAN33 VSTM1 WFDC2
Entrez ID		116449	57017
HPRD ID		14720	13157
Ensembl ID		ENSG00000109684	ENSG00000088682
Uniprot IDs		Q7Z7G1	A0A024R6U3 O75208
PDB IDs			4RHP 6AWL 6DEW
Enriched GO Terms of Interacting Partners?
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