TNNI2 and TNNT1

Number of citations of the paper that reports this interaction (PubMedID 9448267)
11

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		TNNI2	TNNT1
Description		troponin I2, fast skeletal type	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Troponin Complex	Cytosol Troponin Complex
	Molecular Function	Actin Binding Protein Binding Troponin T Binding	Calcium Ion Binding Protein Binding Tropomyosin Binding Calcium-dependent ATPase Activity Troponin T Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Contraction	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases		Distal arthrogryposis (DA)	Nemaline myopathy
GWAS		Celiac disease ( 23936387) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Inflammatory bowel disease ( 23128233) Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Height ( 31562340)
Interacting Genes		13 interacting genes: ACTB CALM1 ESRRA HNF4G PKD2L1 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2	61 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS1 MORF4L1 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		7136	7138
HPRD ID		01843	01841
Ensembl ID		ENSG00000130598	ENSG00000105048
Uniprot IDs		P48788	P13805
PDB IDs		2MKP
Enriched GO Terms of Interacting Partners?
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