TNNI2 and TRIM55

Number of citations of the paper that reports this interaction (PubMedID 18157088)
67

Data Source:
BioGRID (two hybrid)

		TNNI2	TRIM55
Description		troponin I2, fast skeletal type	tripartite motif containing 55
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Troponin Complex	Nucleus Cytoplasm Microtubule
	Molecular Function	Actin Binding Protein Binding Troponin T Binding	Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Contraction	Signal Transduction
Pathways		Striated Muscle Contraction
Drugs
Diseases		Distal arthrogryposis (DA)
GWAS		Celiac disease ( 23936387) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Inflammatory bowel disease ( 23128233) Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)
Interacting Genes		13 interacting genes: ACTB CALM1 ESRRA HNF4G PKD2L1 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2	62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		7136	84675
HPRD ID		01843	05927
Ensembl ID		ENSG00000130598	ENSG00000147573
Uniprot IDs		P48788	Q9BYV6
PDB IDs		2MKP
Enriched GO Terms of Interacting Partners?
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