TRAPPC6A and EFS

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

		TRAPPC6A	EFS
Description		trafficking protein particle complex 6A	embryonal Fyn-associated substrate
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding SH3 Domain Binding Protein Domain Specific Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-PALMITOYL-L-CYSTEINE
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		15 interacting genes: CRYAB EFS HOXA1 IKZF3 RAB3IP RAD54B TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B ZMIZ2 ZNRD2	24 interacting genes: ABI2 APP BCAR1 BLK CRK FYN LYST NCK1 NCK2 NLGN3 NPAS2 NUP155 OSTF1 PTK2 PTK2B PTPN12 SH2D3C SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBC ZNF417
Entrez ID		79090	10278
HPRD ID		14503	09932
Ensembl ID		ENSG00000007255	ENSG00000100842
Uniprot IDs		B7TZ90 O75865	O43281
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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