TRAPPC6A and TRAPPC12

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid)

		TRAPPC6A	TRAPPC12
Description		trafficking protein particle complex 6A	trafficking protein particle complex 12
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Kinetochore Cell Nucleus Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Endopeptidase Activity Protein Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly	Proteolysis ER To Golgi Vesicle-mediated Transport Golgi Organization Metaphase Plate Congression Regulation Of Kinetochore Assembly Positive Regulation Of Protein Localization To Kinetochore
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs		S-PALMITOYL-L-CYSTEINE
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)	Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) ( 29458411)
Interacting Genes		15 interacting genes: CRYAB EFS HOXA1 IKZF3 RAB3IP RAD54B TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B ZMIZ2 ZNRD2	9 interacting genes: FBXO7 MTDH TFCP2 TRAPPC10 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		79090	51112
HPRD ID		14503	15580
Ensembl ID		ENSG00000007255	ENSG00000171853
Uniprot IDs		B7TZ90 O75865	A0A0J9YXQ9 Q8WVT3
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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