TRAPPC6A and ZMIZ2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	ZMIZ2
Description		trafficking protein particle complex 6A	zinc finger MIZ-type containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Factor Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity SUMO Ligase Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly	Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription SMAD Protein Signal Transduction
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-PALMITOYL-L-CYSTEINE
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)	General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		15 interacting genes: CRYAB EFS HOXA1 IKZF3 RAB3IP RAD54B TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B ZMIZ2 ZNRD2	21 interacting genes: AR ARSJ ASB13 BANP C2orf88 CRCP INTS4 LRRC37A11P MCPH1 MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELENOV SOCS6 SSX2 TP53 TRAPPC6A
Entrez ID		79090	83637
HPRD ID		14503	13225
Ensembl ID		ENSG00000007255	ENSG00000122515
Uniprot IDs		B7TZ90 O75865	E7EWM3 Q8NF64
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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