TRAPPC6A and RAB3IP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	RAB3IP
Description		trafficking protein particle complex 6A	RAB3A interacting protein
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Nucleus Cytosol Cytoskeleton Lamellipodium
	Molecular Function	Protein Binding	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly	Protein Targeting To Membrane Ciliary Basal Body-plasma Membrane Docking
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs		S-PALMITOYL-L-CYSTEINE
Diseases
GWAS		Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		15 interacting genes: CRYAB EFS HOXA1 IKZF3 RAB3IP RAD54B TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B ZMIZ2 ZNRD2	21 interacting genes: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A TXNDC5 ZNF410
Entrez ID		79090	117177
HPRD ID		14503	10565
Ensembl ID		ENSG00000007255	ENSG00000127328
Uniprot IDs		B7TZ90 O75865	Q96QF0
PDB IDs		2C0J 2J3T	4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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