ATXN2 and IMPDH2

ATXN2

IMPDH2

Description ataxin 2 inosine monophosphate dehydrogenase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 30013184 31361310)
  • Alopecia areata ( 25608926)
  • Asthma ( 30929738)
  • Asthma (age of onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433 30929738)
  • Asthma onset (childhood vs adult) ( 30929738)
  • Beta-2 microglubulin plasma levels ( 23417110)
  • Blood osmolality (transformed sodium) ( 28360221)
  • Blood pressure ( 21909110)
  • Body mass index ( 26426971)
  • Celiac disease ( 22057235 18311140)
  • Chronic kidney disease ( 20383146)
  • Coronary artery disease ( 29212778 30104761)
  • Crohn's disease ( 26192919 28067908)
  • Diastolic blood pressure ( 26390057 27736895 19430483)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Estimated glomerular filtration rate ( 31152163 31015462)
  • Gastroesophageal reflux disease ( 31527586)
  • Glaucoma (primary open-angle) ( 26752265)
  • Glomerular filtration rate (cystatin C) ( 28452372)
  • Glycated hemoglobin levels ( 28898252)
  • HDL cholesterol ( 30275531)
  • Heart failure ( 31919418)
  • Hematocrit ( 19862010)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Hypertension ( 31879980)
  • Hypothyroidism ( 27182965 22493691)
  • Immature fraction of reticulocytes ( 27863252)
  • Inflammatory bowel disease ( 26192919 28067908)
  • Intraocular pressure ( 30054594)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • LDL cholesterol ( 30275531)
  • Left ventricle diastolic internal dimension ( 28394258)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Mean corpuscular volume ( 27863252)
  • Monocyte count ( 27863252)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Parental longevity (combined parental age at death) ( 29227965)
  • Parental longevity (combined parental attained age, Martingale residuals) ( 29227965)
  • Parental longevity (father's age at death) ( 29227965)
  • Parental longevity (father's attained age) ( 29227965)
  • Parental longevity (mother's attained age) ( 29227965)
  • Peripheral artery disease ( 25009551)
  • Platelet count ( 24026423 29403010 27863252)
  • Platelet distribution width ( 27863252)
  • Plateletcrit ( 27863252)
  • Primary biliary cholangitis ( 26394269)
  • Primary biliary cirrhosis ( 22961000)
  • Primary sclerosing cholangitis ( 23603763)
  • Reaction time ( 29844566)
  • Red blood cell traits ( 23222517)
  • Reticulocyte fraction of red cells ( 27863252)
  • Retinal vascular caliber ( 21060863)
  • Sarcoidosis ( 26051272)
  • Serum total protein level ( 29403010)
  • Sjögren's syndrome ( 24097067)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Sum eosinophil basophil counts ( 27863252)
  • Systemic lupus erythematosus ( 26502338 28714469)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Thyroid peroxidase antibody levels ( 24586183)
  • Thyroid peroxidase antibody positivity ( 24586183)
  • Total cholesterol levels ( 30275531)
  • Urate levels ( 31578528 23263486)
  • Vitiligo ( 27723757)
Interacting Genes 20 interacting genes: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CHGB GFI1B GOLGA6L5P IDH3B IMPDH2 KIFBP LCP1 NCOA4 PABPC1 PLS3 RBFOX1 SH3GL2 SH3GL3 TDRD7 ZNRD1 24 interacting genes: AKT1 ALS2 AMT ANKRD9 APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 KLF7 PIAS4 PRMT1 PXMP2 PXN RAD54L2 RBM15B SUMO4 UBQLN4
Entrez ID 6311 3615
HPRD ID 03307 00895
Ensembl ID ENSG00000204842 ENSG00000178035
Uniprot IDs F8VQP2 Q2M2R5 Q99700 A0A384N6C2 P12268
PDB IDs 3KTR 1B3O 1NF7 1NFB 6I0M 6I0O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?