IMPDH2 and PXMP2

		IMPDH2	PXMP2
Description		inosine monophosphate dehydrogenase 2	peroxisomal membrane protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytoplasm Peroxisomal Membrane Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation Lymphocyte Proliferation Oxidation-reduction Process Retina Development In Camera-type Eye Cellular Response To Interleukin-4	Biological_process
Pathways		Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis	Glyoxylate metabolism and glycine degradation Class I peroxisomal membrane protein import
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-Carboxyamide-Adenine Dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		24 interacting genes: AKT1 ALS2 AMT ANKRD9 APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 KLF7 PIAS4 PRMT1 PXMP2 PXN RAD54L2 RBM15B SUMO4 UBQLN4	4 interacting genes: GOLGA3 IMPDH2 KRT40 SIVA1
Entrez ID		3615	5827
HPRD ID		00895	10176
Ensembl ID		ENSG00000178035	ENSG00000176894
Uniprot IDs		A0A384N6C2 P12268	Q9NR77
PDB IDs		1B3O 1NF7 1NFB 6I0M 6I0O
Enriched GO Terms of Interacting Partners?
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