IMPDH2 and KLF7

		IMPDH2	KLF7
Description		inosine monophosphate dehydrogenase 2	Kruppel like factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nuclear Chromatin Nucleus
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Identical Protein Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Zinc Ion Binding
	Biological Process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation Lymphocyte Proliferation Oxidation-reduction Process Retina Development In Camera-type Eye Cellular Response To Interleukin-4	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Axonogenesis Axon Guidance Glucose Homeostasis Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Dendrite Morphogenesis Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Adipose Tissue Development
Pathways		Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-Carboxyamide-Adenine Dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Diastolic blood pressure ( 30224653) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Lachrymal/Salivary gland lesion in type 1 autoimmune pancreatitis ( 25985088) Red blood cell count ( 27863252) Self-rated health ( 27864402) Smoking status (ever vs never smokers) ( 30643258) Urinary albumin excretion (no hypertensive medication) ( 30220432)
Interacting Genes		24 interacting genes: AKT1 ALS2 AMT ANKRD9 APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 KLF7 PIAS4 PRMT1 PXMP2 PXN RAD54L2 RBM15B SUMO4 UBQLN4	3 interacting genes: APP FBXO38 IMPDH2
Entrez ID		3615	8609
HPRD ID		00895	07279
Ensembl ID		ENSG00000178035	ENSG00000118263
Uniprot IDs		A0A384N6C2 P12268	A0A024R3X8 O75840
PDB IDs		1B3O 1NF7 1NFB 6I0M 6I0O
Enriched GO Terms of Interacting Partners?
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