ATXN2 and ACTN1

  • Number of citations of the paper that reports this interaction (PubMedID 16713569)
  • 313

ATXN2

ACTN1

Description ataxin 2 actinin alpha 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 30013184 31361310)
  • Alopecia areata ( 25608926)
  • Asthma ( 30929738)
  • Asthma (age of onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433 30929738)
  • Asthma onset (childhood vs adult) ( 30929738)
  • Beta-2 microglubulin plasma levels ( 23417110)
  • Blood osmolality (transformed sodium) ( 28360221)
  • Blood pressure ( 21909110)
  • Body mass index ( 26426971)
  • Celiac disease ( 22057235 18311140)
  • Chronic kidney disease ( 20383146)
  • Coronary artery disease ( 29212778 30104761)
  • Crohn's disease ( 26192919 28067908)
  • Diastolic blood pressure ( 26390057 27736895 19430483)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Estimated glomerular filtration rate ( 31152163 31015462)
  • Gastroesophageal reflux disease ( 31527586)
  • Glaucoma (primary open-angle) ( 26752265)
  • Glomerular filtration rate (cystatin C) ( 28452372)
  • Glycated hemoglobin levels ( 28898252)
  • HDL cholesterol ( 30275531)
  • Heart failure ( 31919418)
  • Hematocrit ( 19862010)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Hypertension ( 31879980)
  • Hypothyroidism ( 27182965 22493691)
  • Immature fraction of reticulocytes ( 27863252)
  • Inflammatory bowel disease ( 26192919 28067908)
  • Intraocular pressure ( 30054594)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • LDL cholesterol ( 30275531)
  • Left ventricle diastolic internal dimension ( 28394258)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Mean corpuscular volume ( 27863252)
  • Monocyte count ( 27863252)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Parental longevity (combined parental age at death) ( 29227965)
  • Parental longevity (combined parental attained age, Martingale residuals) ( 29227965)
  • Parental longevity (father's age at death) ( 29227965)
  • Parental longevity (father's attained age) ( 29227965)
  • Parental longevity (mother's attained age) ( 29227965)
  • Peripheral artery disease ( 25009551)
  • Platelet count ( 24026423 29403010 27863252)
  • Platelet distribution width ( 27863252)
  • Plateletcrit ( 27863252)
  • Primary biliary cholangitis ( 26394269)
  • Primary biliary cirrhosis ( 22961000)
  • Primary sclerosing cholangitis ( 23603763)
  • Reaction time ( 29844566)
  • Red blood cell traits ( 23222517)
  • Reticulocyte fraction of red cells ( 27863252)
  • Retinal vascular caliber ( 21060863)
  • Sarcoidosis ( 26051272)
  • Serum total protein level ( 29403010)
  • Sjögren's syndrome ( 24097067)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Sum eosinophil basophil counts ( 27863252)
  • Systemic lupus erythematosus ( 26502338 28714469)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Thyroid peroxidase antibody levels ( 24586183)
  • Thyroid peroxidase antibody positivity ( 24586183)
  • Total cholesterol levels ( 30275531)
  • Urate levels ( 31578528 23263486)
  • Vitiligo ( 27723757)
Interacting Genes 20 interacting genes: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CHGB GFI1B GOLGA6L5P IDH3B IMPDH2 KIFBP LCP1 NCOA4 PABPC1 PLS3 RBFOX1 SH3GL2 SH3GL3 TDRD7 ZNRD1 79 interacting genes: ACTN2 ACTN3 ADORA2A APC ATXN2 ATXN7 CACNA1A CAMK2A CBY2 CDK5 CDK5R1 CDK5R2 CLIC5 COIL COL17A1 CSRP1 CSRP3 CTNNA1 DDIAS EPM2AIP1 ERBIN FBP1 FXN GFI1B GIPC1 GIT2 GRIA4 GRIN2A GRM5 GTF2H1 HSPB1 ICAM5 ITGB1 KAT2B KCTD6 KPNA2 LPP MAGEA11 MAP2 MAP3K1 MED14 MICALL2 MTDH MTNR1A MTNR1B MYOT MYOZ1 MYOZ2 MYOZ3 NEBL NR1H3 NUMBL OAS1 PALLD PDHX PDLIM1 PDLIM5 PIAS4 PKD1 PKN1 PLD2 PSEN1 PSMA1 PTK2 PTPN1 PTPN6 PYGB RAVER1 RPS27 SIRPA SLC2A4 SORBS2 SRC SSX2IP TES TTN VCL XRCC4 ZYX
Entrez ID 6311 87
HPRD ID 03307 00020
Ensembl ID ENSG00000204842 ENSG00000072110
Uniprot IDs F8VQP2 Q2M2R5 Q99700 A0A024R694 P12814
PDB IDs 3KTR 2EYI 2EYN 2N8Y 2N8Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?