IMPDH2 and RAD54L2

		IMPDH2	RAD54L2
Description		inosine monophosphate dehydrogenase 2	RAD54 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Identical Protein Binding Metal Ion Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding
	Biological Process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation Lymphocyte Proliferation Oxidation-reduction Process Retina Development In Camera-type Eye Cellular Response To Interleukin-4	DNA Duplex Unwinding
Pathways		Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-Carboxyamide-Adenine Dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		24 interacting genes: AKT1 ALS2 AMT ANKRD9 APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 KLF7 PIAS4 PRMT1 PXMP2 PXN RAD54L2 RBM15B SUMO4 UBQLN4	20 interacting genes: AR ATN1 ATXN1 ATXN1L CNOT7 IMPDH2 NR3C1 NR5A1 NR5A2 PIAS1 PPARG PSMA3 RBPMS RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 UBE2I
Entrez ID		3615	23132
HPRD ID		00895	10018
Ensembl ID		ENSG00000178035	ENSG00000164080
Uniprot IDs		A0A384N6C2 P12268	B3KV54 Q9Y4B4
PDB IDs		1B3O 1NF7 1NFB 6I0M 6I0O
Enriched GO Terms of Interacting Partners?
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