PSEN2 and EXOC6

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 33
  • Data Source:
  • BioGRID (two hybrid)

PSEN2

EXOC6

Description presenilin 2 exocyst complex component 6
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325)
  • Body mass index ( 28892062)
  • Coronary artery disease ( 29212778)
  • Estimated glomerular filtration rate ( 31015462)
  • Glaucoma (primary open-angle) ( 29449654)
  • Hemoglobin A1c levels ( 29403010)
  • High density lipoprotein cholesterol levels ( 29403010)
  • Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273)
  • Intraocular pressure ( 30054594)
  • Metabolic syndrome ( 31589552)
  • Total bilirubin levels ( 29403010)
Interacting Genes 61 interacting genes: AAMP ACTG1 AP1G1 APH1A APH1B APP AURKA BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HLA-DMB HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OGA PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 11 interacting genes: APP CYP2C8 ECSIT EXOSC1 GCDH LOXL4 MAST1 NOS3 PRDX2 PSEN2 RNF32
Entrez ID 5664 54536
HPRD ID 02860 10216
Ensembl ID ENSG00000143801 ENSG00000138190
Uniprot IDs P49810 A5YP36 B2RDH5 B3KXY5 B7Z6G5 E7EW84 Q8TAG9
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?