PSEN2 and FLNB

  • Number of citations of the paper that reports this interaction (PubMedID 9437013)
  • 21
  • Data Source:
  • BioGRID (two hybrid, pull down)
  • HPRD (two hybrid, in vitro, in vivo)

PSEN2

FLNB

Description presenilin 2 filamin B
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065)
  • Eating disorders (purging via substances) ( 23568457)
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Height ( 31217584)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Immature fraction of reticulocytes ( 27863252)
  • Optic cup area ( 25631615 31798171 28073927)
  • Pulse pressure ( 30578418)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
  • Systemic sclerosis ( 31672989)
  • Vertical cup-disc ratio ( 28073927)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 61 interacting genes: AAMP ACTG1 AP1G1 APH1A APH1B APP AURKA BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HLA-DMB HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OGA PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 20 interacting genes: ASB2 ATF7IP FBLIM1 FLNA GP1BA HSPB1 ITGB1 ITGB3 ITGB6 MLH1 NPHP1 PLEKHO1 PSEN1 PSEN2 PTEN RAD21 SMURF2 TRIM55 TSC22D2 TSHR
Entrez ID 5664 2317
HPRD ID 02860 04543
Ensembl ID ENSG00000143801 ENSG00000136068
Uniprot IDs P49810 O75369
PDB IDs 2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L 5DCP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?