EXOC6 and PRDX2

Number of citations of the paper that reports this interaction (PubMedID 21163940)
33

Data Source:
BioGRID (two hybrid)

		EXOC6	PRDX2
Description		exocyst complex component 6	peroxiredoxin 2
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane Growth Cone Perinuclear Region Of Cytoplasm Flemming Body	Cell Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Thioredoxin Peroxidase Activity Antioxidant Activity
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport	Activation Of MAPK Activity Respiratory Burst Involved In Inflammatory Response Response To Oxidative Stress Regulation Of Hydrogen Peroxide Metabolic Process Removal Of Superoxide Radicals Positive Regulation Of Blood Coagulation Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Response To Lipopolysaccharide Cellular Response To Stress Cellular Response To Oxidative Stress T Cell Proliferation Hydrogen Peroxide Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Leukocyte Activation Cell Redox Homeostasis Negative Regulation Of T Cell Differentiation Thymus Development Homeostasis Of Number Of Cells Oxidation-reduction Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Detoxification of Reactive Oxygen Species TP53 Regulates Metabolic Genes Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs			3-Sulfinoalanine N-Carbamoyl-Alanine Copper
Diseases
GWAS		Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Body mass index ( 28892062) Coronary artery disease ( 29212778) Estimated glomerular filtration rate ( 31015462) Glaucoma (primary open-angle) ( 29449654) Hemoglobin A1c levels ( 29403010) High density lipoprotein cholesterol levels ( 29403010) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273) Intraocular pressure ( 30054594) Metabolic syndrome ( 31589552) Total bilirubin levels ( 29403010)
Interacting Genes		11 interacting genes: APP CYP2C8 ECSIT EXOSC1 GCDH LOXL4 MAST1 NOS3 PRDX2 PSEN2 RNF32	24 interacting genes: A2M APOE APP BAD CA4 CD320 CDC37 COPS5 ECSIT EXOC6 IFIT5 MAST1 NLGN3 PDGFRB PPP2R1A PPP2R1B PRDX4 PSEN1 RNF32 SAT1 SUMO4 TXNDC5 UTY YWHAZ
Entrez ID		54536	7001
HPRD ID		10216	02763
Ensembl ID		ENSG00000138190	ENSG00000167815
Uniprot IDs		A5YP36 B2RDH5 B3KXY5 B7Z6G5 E7EW84 Q8TAG9	P32119 V9HW12
PDB IDs			1QMV 5B8A 5B8B 5IJT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?