PSEN2 and DOCK3

  • Number of citations of the paper that reports this interaction (PubMedID 10854253)
  • 24
  • Data Source:
  • HPRD (two hybrid, in vitro)

PSEN2

DOCK3

Description presenilin 2 dedicator of cytokinesis 3
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bacteremia ( 27236921)
  • Blood protein levels ( 28240269)
  • Body fat distribution (arm fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body fat mass ( 28552196)
  • Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
  • Cocaine dependence ( 31212010)
  • Colorectal cancer ( 29228715)
  • Depressive symptom (appetite changes) (binary trait) ( 31530331)
  • Depressive symptoms (binary sum-score) ( 31530331)
  • Depressive symptoms (sum-score) ( 31530331)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Estimated glomerular filtration rate ( 31152163)
  • Height ( 20881960 25282103)
  • Melanoma ( 24980573)
  • Morning person ( 30696823)
  • Sum eosinophil basophil counts ( 27863252)
  • Trunk fat mass ( 28552196)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
Interacting Genes 61 interacting genes: AAMP ACTG1 AP1G1 APH1A APH1B APP AURKA BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HLA-DMB HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OGA PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 7 interacting genes: CALM1 CRK KHDRBS1 NR3C1 PSEN1 PSEN2 SRPK2
Entrez ID 5664 1795
HPRD ID 02860 10341
Ensembl ID ENSG00000143801 ENSG00000088538
Uniprot IDs P49810 Q8IZD9
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?