EXOC6 and NOS3

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 33
  • Data Source:
  • BioGRID (two hybrid)

EXOC6

NOS3

Description exocyst complex component 6 nitric oxide synthase 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325)
  • Body mass index ( 28892062)
  • Coronary artery disease ( 29212778)
  • Estimated glomerular filtration rate ( 31015462)
  • Glaucoma (primary open-angle) ( 29449654)
  • Hemoglobin A1c levels ( 29403010)
  • High density lipoprotein cholesterol levels ( 29403010)
  • Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273)
  • Intraocular pressure ( 30054594)
  • Metabolic syndrome ( 31589552)
  • Total bilirubin levels ( 29403010)
  • Coronary artery disease ( 29212778 30104761 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Diastolic blood pressure ( 27841878 28739976 27618448)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Estimated glomerular filtration rate ( 31451708)
  • Eyebrow thickness ( 26926045)
  • Hypertension ( 27618448)
  • Mean arterial pressure ( 27618448)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Offspring birth weight ( 31043758)
  • Stroke ( 30383316)
  • Systolic blood pressure ( 27841878 27618448 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 11 interacting genes: APP CYP2C8 ECSIT EXOSC1 GCDH LOXL4 MAST1 NOS3 PRDX2 PSEN2 RNF32 46 interacting genes: A2M ACTN2 ACTN4 AGTR1 AKT1 APOE APP BDKRB2 BDNF CALM1 CAV1 CDC37 CEP55 EDNRB EFEMP1 EFEMP2 ELAVL1 ELAVL3 EXOC6 EXOSC1 FIS1 GCDH GOLGA2 H3-3A HSP90AA1 HTRA1 IMMT KANK2 MAGEA11 MAST1 MPRIP NMT1 NOSIP NOSTRIN PAXIP1 PI4K2A PPP2R5A PSEN1 PSEN2 RNF31 RNF32 SP1 ST13 TECR TXNDC11 UMPS
Entrez ID 54536 4846
HPRD ID 10216 01224
Ensembl ID ENSG00000138190 ENSG00000164867
Uniprot IDs A5YP36 B2RDH5 B3KXY5 B7Z6G5 E7EW84 Q8TAG9 A0S0A6 P29474
PDB IDs 1M9J 1M9K 1M9M 1M9Q 1M9R 1NIW 2LL7 2MG5 2N8J 3EAH 3NOS 4D1O 4D1P 5UO8 5UO9 5UOA 5UOB 5UOC 5VVB 5VVC 5VVD 5XOF 6AV6 6AV7 6CIE 6CIF 6NH1 6NH2 6NH3 6NH4 6NH5 6NH6 6NH7 6NH8 6NHF
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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