PSEN2 and APH1B

  • Number of citations of the paper that reports this interaction (PubMedID 12297508)
  • 55
  • Data Source:
  • HPRD (in vivo, in vitro)

PSEN2

APH1B

Description presenilin 2 aph-1 homolog B, gamma-secretase subunit
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Estimated glomerular filtration rate ( 31152163)
  • Family history of Alzheimer's disease ( 30617256)
  • Metabolite levels ( 23823483)
  • Myopia ( 27182965)
  • Response to fenofibrate (triglyceride levels) ( 27002377)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 61 interacting genes: AAMP ACTG1 AP1G1 APH1A APH1B APP AURKA BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HLA-DMB HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OGA PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 3 interacting genes: NCSTN PSEN1 PSEN2
Entrez ID 5664 83464
HPRD ID 02860 06361
Ensembl ID ENSG00000143801 ENSG00000138613
Uniprot IDs P49810 Q8WW43
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?