PSEN2 and SPC24

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 33
  • Data Source:
  • BioGRID (two hybrid)

PSEN2

SPC24

Description presenilin 2 SPC24 component of NDC80 kinetochore complex
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cortisol levels (saliva) ( 28843169)
  • HDL cholesterol ( 23505323)
  • Intraocular pressure ( 29617998)
  • Lipid traits ( 24386095)
  • Low density lipoprotein cholesterol levels ( 30718733)
  • Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 31095298)
Interacting Genes 61 interacting genes: AAMP ACTG1 AP1G1 APH1A APH1B APP AURKA BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HLA-DMB HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OGA PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1 5 interacting genes: APP PSEN2 SKA1 SKA2 SKA3
Entrez ID 5664 147841
HPRD ID 02860 15464
Ensembl ID ENSG00000143801 ENSG00000161888
Uniprot IDs P49810 B4E086 Q8NBT2
PDB IDs 2VE7 3IZ0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?