TRIM41 and EHHADH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM41	EHHADH
Description		tripartite motif containing 41	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Nuclear Body	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Enzyme Binding
	Biological Process	Protein Ubiquitination Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Internal Protein Amino Acid Acetylation Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs			NADH
Diseases
GWAS			Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)
Interacting Genes		62 interacting genes: AEN AKTIP APP BRAP CEP44 CHD2 CSNK2A2 DEPTOR EHHADH FAM124A FRA10AC1 GPATCH2L IKBKG KIFC3 KRTAP10-9 MAGEH1 MEOX2 MORF4L1 MPP3 NCK2 NEDD4L NOD2 PHC2 PHF7 PRKCA PRKCB PRPF31 PUS7L RNPS1 SORBS3 SRPK2 TLE5 TOP3B TRAIP TRIM17 TRIM26 TRIM4 TRIM52 UBE2D2 UBE2I ZBTB24 ZBTB38 ZBTB48 ZBTB8A ZFP2 ZFP64 ZNF138 ZNF24 ZNF250 ZNF26 ZNF263 ZNF264 ZNF266 ZNF329 ZNF417 ZNF473 ZNF490 ZNF564 ZNF587 ZNF670 ZSCAN21 ZSCAN26	27 interacting genes: ACTB ACTG1 BHLHE40 CAT CBS CCDC102B DES FUNDC1 KCTD6 KCTD9 KRTAP10-7 LZTS2 MID1 NECAB2 PNMA1 SCP2 SSNA1 SSX2IP TNIP1 TPP2 TRAF1 TRIM27 TRIM41 TRIM54 TRIM55 TRIM63 ZBTB9
Entrez ID		90933	1962
HPRD ID		15558	06125
Ensembl ID		ENSG00000146063	ENSG00000113790
Uniprot IDs		Q8WV44	Q08426
PDB IDs		2EGM
Enriched GO Terms of Interacting Partners?
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