TRIM41 and AEN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM41	AEN
Description		tripartite motif containing 41	apoptosis enhancing nuclease
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Nuclear Body	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding	Nucleic Acid Binding Exonuclease Activity Protein Binding
	Biological Process	Protein Ubiquitination Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	DNA Catabolic Process, Exonucleolytic RNA Catabolic Process Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Viral Genome Replication Defense Response To Virus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)
Interacting Genes		62 interacting genes: AEN AKTIP APP BRAP CEP44 CHD2 CSNK2A2 DEPTOR EHHADH FAM124A FRA10AC1 GPATCH2L IKBKG KIFC3 KRTAP10-9 MAGEH1 MEOX2 MORF4L1 MPP3 NCK2 NEDD4L NOD2 PHC2 PHF7 PRKCA PRKCB PRPF31 PUS7L RNPS1 SORBS3 SRPK2 TLE5 TOP3B TRAIP TRIM17 TRIM26 TRIM4 TRIM52 UBE2D2 UBE2I ZBTB24 ZBTB38 ZBTB48 ZBTB8A ZFP2 ZFP64 ZNF138 ZNF24 ZNF250 ZNF26 ZNF263 ZNF264 ZNF266 ZNF329 ZNF417 ZNF473 ZNF490 ZNF564 ZNF587 ZNF670 ZSCAN21 ZSCAN26	34 interacting genes: CRTC3 EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473
Entrez ID		90933	64782
HPRD ID		15558	08573
Ensembl ID		ENSG00000146063	ENSG00000181026
Uniprot IDs		Q8WV44	Q8WTP8
PDB IDs		2EGM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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