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CD79A and TMEM86B
Data Source:
BioGRID
(two hybrid)
CD79A
TMEM86B
Description
CD79a molecule
transmembrane protein 86B
Image
No pdb structure
GO Annotations
Cellular Component
Multivesicular Body
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
B Cell Receptor Complex
Membrane Raft
Cytoplasm
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Identical Protein Binding
Protein Binding
Ether Hydrolase Activity
Identical Protein Binding
Alkenylglycerophosphocholine Hydrolase Activity
Alkenylglycerophosphoethanolamine Hydrolase Activity
Biological Process
Adaptive Immune Response
B Cell Differentiation
B Cell Proliferation
B Cell Activation
B Cell Receptor Signaling Pathway
Phosphatidylcholine Acyl-chain Remodeling
Ether Lipid Metabolic Process
Pathways
CD22 mediated BCR regulation
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Acyl chain remodelling of PC
Drugs
Diseases
Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS
Brain morphology (MOSTest) (
32665545
)
Mean reticulocyte volume (
32888494
)
Phosphatidylethanolamine-ether levels (
31551469
)
Systemic lupus erythematosus (
33536424
28714469
)
Interacting Genes
181 interacting genes:
ADIPOQ
AGTRAP
ALG10
ALG10B
ALG3
APOD
AQP1
AQP3
ATP6V0C
BCL2L2
BET1
BLK
BLNK
BRICD5
BTN2A2
C14orf180
C1GALT1
C2CD2L
C4orf3
CCDC167
CD19
CD5
CD79B
CDIPT
CLDN1
CLN6
CMTM5
CMTM7
CNIH1
CNIH3
COL4A5
CTSA
CTXN3
CYB561
CYB561A3
CYB561D2
CYB5B
DEFB127
DOLK
EDDM3B
EMC6
EMP1
EMP3
FA2H
FAM241B
FANCA
FATE1
FAXDC2
FCAR
FDFT1
FFAR3
FKBP8
FUNDC2
FXYD3
FYN
GALNT15
GIMAP1
GJB1
GPR42
HACD4
HCLS1
HMOX1
HMOX2
IER3
IGHM
INSIG2
ITGAM
JAGN1
JCHAIN
LAMB1
LCK
LEPROTL1
LHFPL5
LPAR3
LTC4S
LYN
MALL
MARCHF2
MFF
MFSD12
MFSD5
MFSD6
MGLL
MMD2
MOSPD3
MS4A13
MYADM
MYADML2
NAT8
NEU1
NINJ2
NIPAL3
NKG7
ORMDL2
OTOP2
PGAP2
PIGR
PKMYT1
PLP2
PLPP6
PLPPR2
PNLIPRP1
PRAF2
PTCH1
PTPN6
REEP6
RHO
RTP2
SACM1L
SEC22B
SERP1
SFTPC
SLC13A4
SLC13A5
SLC16A12
SLC16A13
SLC30A2
SLC35B1
SLC35B4
SLC38A1
SLC39A2
SLC39A9
SLC41A1
SLC41A2
SLC46A3
SLC66A2
SLC6A12
SLC7A1
SMCO4
SMIM3
STRIT1
STX12
STX3
STX8
SYK
SYNJ2BP
TECR
THBD
TM4SF19
TM4SF4
TMBIM6
TMEM107
TMEM11
TMEM128
TMEM140
TMEM147
TMEM14B
TMEM176A
TMEM187
TMEM19
TMEM218
TMEM222
TMEM229B
TMEM239
TMEM243
TMEM254
TMEM262
TMEM42
TMEM86A
TMEM86B
TMPPE
TNFRSF10C
TRAM1L1
TRARG1
TSNARE1
TSPAN2
TSPO2
UBE2J1
UBIAD1
UNC93B1
VAMP3
VAPA
VAPB
VTI1B
WFDC2
WFS1
YIF1A
YIPF4
YIPF6
ZDHHC15
ZDHHC22
105 interacting genes:
AQP6
ARL13B
ARL6IP6
ASGR2
BCL2L13
BIK
BMP10
C2CD2L
CCDC167
CCDC34
CCL4
CD53
CD79A
CLRN1
CYB5B
DHRSX
DNAJC30
EBP
ERGIC3
ERP29
EVI2B
F11R
FAM209A
FAXDC2
FKBP7
FXYD6
GJA1
GJA4
GJA8
GOLM1
GPR37L1
GPX8
GUCA2A
HIBADH
HSD17B13
IER3IP1
IFITM3
KIR2DL3
LAPTM4B
LIME1
LSS
LY6D
MARCHF2
MFF
MGST3
MMGT1
MS4A14
MSMO1
MUC1
NDUFAF1
NEMP1
NINJ2
ORMDL2
OTULINL
PEX11G
PGRMC2
PIGF
PLN
PSCA
PTPN1
PTPN9
RHBDD1
RHOT2
RPRM
RTP2
SEC22B
SERINC2
SFRP1
SFT2D1
SFXN5
SLC10A6
SLC29A2
SLC35G2
SLC39A9
SMIM1
SNORC
SSMEM1
STOM
STX12
STX6
STX8
TEX29
THAP4
THBD
TIMM23
TMEM106A
TMEM107
TMEM120A
TMEM14A
TMEM14C
TMEM203
TMEM237
TMEM248
TMEM52B
TMEM60
TMPRSS2
TMX2
TREX1
TSNARE1
USE1
VAMP2
VAMP3
VAMP5
VAPA
ZDHHC22
Entrez ID
973
255043
HPRD ID
00203
14540
Ensembl ID
ENSG00000105369
ENSG00000180089
Uniprot IDs
P11912
Q8N661
PDB IDs
1CV9
Enriched GO Terms of Interacting Partners
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