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CD79A and FXYD3
Data Source:
BioGRID
(two hybrid)
CD79A
FXYD3
Description
CD79a molecule
FXYD domain containing ion transport regulator 3
Image
No pdb structure
GO Annotations
Cellular Component
Multivesicular Body
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
B Cell Receptor Complex
Membrane Raft
Plasma Membrane
Integral Component Of Plasma Membrane
Extracellular Exosome
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Identical Protein Binding
Chloride Channel Activity
Sodium Channel Regulator Activity
Ion Channel Regulator Activity
Biological Process
Adaptive Immune Response
B Cell Differentiation
B Cell Proliferation
B Cell Activation
B Cell Receptor Signaling Pathway
Potassium Ion Transport
Sodium Ion Transport
Chloride Transport
Ion Transmembrane Transport
Chloride Transmembrane Transport
Regulation Of Cardiac Conduction
Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
CD22 mediated BCR regulation
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Ion homeostasis
Ion transport by P-type ATPases
Potential therapeutics for SARS
Drugs
Diseases
Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
181 interacting genes:
ADIPOQ
AGTRAP
ALG10
ALG10B
ALG3
APOD
AQP1
AQP3
ATP6V0C
BCL2L2
BET1
BLK
BLNK
BRICD5
BTN2A2
C14orf180
C1GALT1
C2CD2L
C4orf3
CCDC167
CD19
CD5
CD79B
CDIPT
CLDN1
CLN6
CMTM5
CMTM7
CNIH1
CNIH3
COL4A5
CTSA
CTXN3
CYB561
CYB561A3
CYB561D2
CYB5B
DEFB127
DOLK
EDDM3B
EMC6
EMP1
EMP3
FA2H
FAM241B
FANCA
FATE1
FAXDC2
FCAR
FDFT1
FFAR3
FKBP8
FUNDC2
FXYD3
FYN
GALNT15
GIMAP1
GJB1
GPR42
HACD4
HCLS1
HMOX1
HMOX2
IER3
IGHM
INSIG2
ITGAM
JAGN1
JCHAIN
LAMB1
LCK
LEPROTL1
LHFPL5
LPAR3
LTC4S
LYN
MALL
MARCHF2
MFF
MFSD12
MFSD5
MFSD6
MGLL
MMD2
MOSPD3
MS4A13
MYADM
MYADML2
NAT8
NEU1
NINJ2
NIPAL3
NKG7
ORMDL2
OTOP2
PGAP2
PIGR
PKMYT1
PLP2
PLPP6
PLPPR2
PNLIPRP1
PRAF2
PTCH1
PTPN6
REEP6
RHO
RTP2
SACM1L
SEC22B
SERP1
SFTPC
SLC13A4
SLC13A5
SLC16A12
SLC16A13
SLC30A2
SLC35B1
SLC35B4
SLC38A1
SLC39A2
SLC39A9
SLC41A1
SLC41A2
SLC46A3
SLC66A2
SLC6A12
SLC7A1
SMCO4
SMIM3
STRIT1
STX12
STX3
STX8
SYK
SYNJ2BP
TECR
THBD
TM4SF19
TM4SF4
TMBIM6
TMEM107
TMEM11
TMEM128
TMEM140
TMEM147
TMEM14B
TMEM176A
TMEM187
TMEM19
TMEM218
TMEM222
TMEM229B
TMEM239
TMEM243
TMEM254
TMEM262
TMEM42
TMEM86A
TMEM86B
TMPPE
TNFRSF10C
TRAM1L1
TRARG1
TSNARE1
TSPAN2
TSPO2
UBE2J1
UBIAD1
UNC93B1
VAMP3
VAPA
VAPB
VTI1B
WFDC2
WFS1
YIF1A
YIPF4
YIPF6
ZDHHC15
ZDHHC22
64 interacting genes:
AGR3
ANK1
AQP6
AQP9
BCL2L13
BEST2
CD79A
CNR2
CREB3
CREB3L1
CYB5R3
EBP
ERG28
ERGIC3
FAM209A
FBXL12
FCGR2A
FFAR2
GHITM
GPR152
GPR37L1
GPR42
GPRC5D
IBSP
KASH5
KCNN4
LMNA
LTC4S
MAPK6
MFSD11
MFSD5
MGST1
MTIF3
NR4A1
NUDT3
PLPP6
SCN3B
SERBP1
SGPL1
SLC10A1
SLC10A6
SLC16A12
SLC18A1
SLC1A1
SLC30A2
SLC35A1
SLC35B1
SLC35C2
SLC39A2
SPNS3
STRIT1
STX3
TIMM23
TIMMDC1
TLCD1
TMBIM6
TMEM179B
TMEM50B
TMEM52B
TMEM80
TMEM86A
TMEM97
TSPO2
XKR3
Entrez ID
973
5349
HPRD ID
00203
05410
Ensembl ID
ENSG00000105369
ENSG00000089356
Uniprot IDs
P11912
Q14802
PDB IDs
1CV9
Enriched GO Terms of Interacting Partners
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