ZNF646 and NINL

Data Source:
HPRD (two hybrid)

		ZNF646	NINL
Description		zinc finger protein 646	ninein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Centrosome Cytosol Microtubule Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Parkinson's disease ( 28892059)	Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)
Interacting Genes		7 interacting genes: EMSY LEUTX MDFI NINL PRKG1 TRAF2 UBE2I	51 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		9726	22981
HPRD ID		15886	11120
Ensembl ID		ENSG00000167395	ENSG00000101004
Uniprot IDs		O15015	Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?
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