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SDC3 and TMEM218
Data Source:
BioGRID
(two hybrid)
SDC3
TMEM218
Description
syndecan 3
transmembrane protein 218
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Lumen
Plasma Membrane
Cell Surface
Membrane
Integral Component Of Membrane
Lysosomal Lumen
Microspike
Collagen-containing Extracellular Matrix
Cilium
Integral Component Of Membrane
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Retinoid Metabolic Process
Glycosaminoglycan Biosynthetic Process
Glycosaminoglycan Catabolic Process
Cell Migration
Leukocyte Migration
Pathways
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Syndecan interactions
Syndecan interactions
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective EXT2 causes exostoses 2
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Defective B3GALT6 causes EDSP2 and SEMDJL1
Retinoid metabolism and transport
Drugs
Diseases
GWAS
Loneliness (
27629369
)
Breast cancer (survival) (
25890600
)
Familial lung adenocarcinoma (
29924316
)
Interacting Genes
32 interacting genes:
AGR2
CASK
CMTM7
COL5A1
CSK
CTTN
CUX1
EPHB4
FGF2
FYN
ITGB4
KCNJ2
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP2-3
KRTAP2-4
KRTAP4-2
KRTAP5-7
KRTAP5-9
KRTAP9-2
LCE3D
MDK
PLN
PTN
SLC35A1
SMIM1
TMEM14C
TMEM218
TUBA1A
TUBB
TUBB2A
72 interacting genes:
APH1A
AQP2
AQP6
ARL13B
ASZ1
ATP6V0E1
BSCL2
CD300A
CD53
CD79A
CLDN2
CLEC10A
CLEC17A
CPLX4
CREB3L1
CTLA4
DAGLA
EBP
ELOVL2
ELOVL4
EMP1
ERGIC3
FAM209A
FCER1G
FRMD3
GDAP1
GJB1
GJB4
GJB6
GPR152
GPR61
GPX8
IFNGR2
KCNJ6
KCNK5
KIR2DL3
LDLRAD1
LHFPL5
LMNA
LSMEM2
MFF
MS4A3
MTIF3
NPFFR2
PCNA
PDCD1LG2
PIK3IP1
PLEKHO1
PSCA
RETREG3
SAR1A
SDC3
SLC10A4
SLC10A6
SLC18A1
SMIM3
SSMEM1
TM4SF18
TMED8
TMEM106C
TMEM182
TMEM207
TMEM234
TMEM31
TMEM45B
TMEM52B
TMEM88
TMPRSS2
TRHR
TSPAN12
TSPAN18
VSIR
Entrez ID
9672
219854
HPRD ID
01719
19054
Ensembl ID
ENSG00000162512
ENSG00000150433
Uniprot IDs
O75056
A2RU14
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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